Recombinant human collagen freeze-dried powder and preparation method thereof

The invention relates to recombinant human collagen freeze-dried powder and a preparation method thereof. The recombinant human collagen freeze-dried powder comprises recombinant human collagen, a stabilizing agent, an auxiliary agent and a buffering agent, wherein the buffering agent comprises EDTA...

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Bibliographische Detailangaben
Hauptverfasser: LEI DENGFENG, GAO HEYI, LIU ANHONG, ZENG SA, TANG JIE, XUE YONGYONG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to recombinant human collagen freeze-dried powder and a preparation method thereof. The recombinant human collagen freeze-dried powder comprises recombinant human collagen, a stabilizing agent, an auxiliary agent and a buffering agent, wherein the buffering agent comprises EDTA-2Na, bovine serum albumin, phosphate, sodium chloride and Tween 80. Wherein the stabilizing agent, the auxiliary agent and the buffering agent all play a role in maintaining the stability of the recombinant human collagen, and particularly, the EDTA-2Na, the bovine serum albumin, the phosphate, the sodium chloride and the Tween 80 are mutually matched and have synergistic interaction, so that the stability of the recombinant human collagen is remarkably improved, and the biological activity of the recombinant human collagen can be kept for a long time. The recombinant human collagen freeze-dried powder provided by the invention can be preserved for 12 months at normal temperature, keeps good biological activity, c