A METHOD FOR DETECTING A PROSTATE CANCER BIOMARKER

A METHOD FOR DETECTING A PROSTATE CANCER BIOMARKER

The present disclosure relates to a method for detecting a prostate cancer related biomarker, comprising contacting the diluted sample with a modulating agent selected from a group consisting of sodium, 3-hydroxy-4-[(2-hydroxynaphthalen-1-yl)diazenyl]naphthalene-1-sulfonate, sodium, 3-hydroxy-4-[(1-...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: PAAVILAINEN SUSANNA, KULPAKKO JANNE, VEPSALAINEN JOUKO
Format: Patent
Sprache:chi ; eng
Schlagworte:
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator PAAVILAINEN SUSANNA
KULPAKKO JANNE
VEPSALAINEN JOUKO
description The present disclosure relates to a method for detecting a prostate cancer related biomarker, comprising contacting the diluted sample with a modulating agent selected from a group consisting of sodium, 3-hydroxy-4-[(2-hydroxynaphthalen-1-yl)diazenyl]naphthalene-1-sulfonate, sodium, 3-hydroxy-4-[(1-hydroxynaphthalen-2-yl)diazenyl]-7-nitronaphthalene-1-sulfonate, triisopropylsilane, and iron(III) chloride, and a luminescent label to obtain a measurement sample. Then, the measurement sample is incubated for a period of time and excited thereafter. Time-resolved luminescence signal of the label in the measurement sample is measured, leading to an increased likelihood of prostate cancer of the human subject if the luminescence signal is at least 50 % higher than for a control sample from a human subject without prostate cancer. 本公开涉及用于检测前列腺癌相关生物标志物的方法，包括将经稀释样品与调节剂和发光标签接触以获得测量样品，所述调节剂选自由钠；3-羟基-4-[(2-羟基萘-1-基)二氮烯基]萘-1-磺酸酯、钠；3-羟基-4-[(1-羟基萘-2-基)二氮烯基]-7-硝基萘-1-磺酸酯、三异丙基硅烷，和氯化铁(III)组成的组。然后，将测量样品孵育一段时间，并随后进行激发。测量所述测量样品中所述标
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN113984720A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN113984720A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN113984720A3</originalsourceid><addsrcrecordid>eNrjZDByVPB1DfHwd1Fw8w9ScHENcXUO8fRzV3BUCAjyDw5xDHFVcHb0c3YNUnDy9Pd1DPJ2DeJhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfHOfoaGxpYWJuZGBo7GxKgBAEspJno</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>A METHOD FOR DETECTING A PROSTATE CANCER BIOMARKER</title><source>esp@cenet</source><creator>PAAVILAINEN SUSANNA ; KULPAKKO JANNE ; VEPSALAINEN JOUKO</creator><creatorcontrib>PAAVILAINEN SUSANNA ; KULPAKKO JANNE ; VEPSALAINEN JOUKO</creatorcontrib><description>The present disclosure relates to a method for detecting a prostate cancer related biomarker, comprising contacting the diluted sample with a modulating agent selected from a group consisting of sodium, 3-hydroxy-4-[(2-hydroxynaphthalen-1-yl)diazenyl]naphthalene-1-sulfonate, sodium, 3-hydroxy-4-[(1-hydroxynaphthalen-2-yl)diazenyl]-7-nitronaphthalene-1-sulfonate, triisopropylsilane, and iron(III) chloride, and a luminescent label to obtain a measurement sample. Then, the measurement sample is incubated for a period of time and excited thereafter. Time-resolved luminescence signal of the label in the measurement sample is measured, leading to an increased likelihood of prostate cancer of the human subject if the luminescence signal is at least 50 % higher than for a control sample from a human subject without prostate cancer. 本公开涉及用于检测前列腺癌相关生物标志物的方法，包括将经稀释样品与调节剂和发光标签接触以获得测量样品，所述调节剂选自由钠；3-羟基-4-[(2-羟基萘-1-基)二氮烯基]萘-1-磺酸酯、钠；3-羟基-4-[(1-羟基萘-2-基)二氮烯基]-7-硝基萘-1-磺酸酯、三异丙基硅烷，和氯化铁(III)组成的组。然后，将测量样品孵育一段时间，并随后进行激发。测量所述测量样品中所述标</description><language>chi ; eng</language><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; PHYSICS ; TESTING</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220128&amp;DB=EPODOC&amp;CC=CN&amp;NR=113984720A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220128&amp;DB=EPODOC&amp;CC=CN&amp;NR=113984720A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PAAVILAINEN SUSANNA</creatorcontrib><creatorcontrib>KULPAKKO JANNE</creatorcontrib><creatorcontrib>VEPSALAINEN JOUKO</creatorcontrib><title>A METHOD FOR DETECTING A PROSTATE CANCER BIOMARKER</title><description>The present disclosure relates to a method for detecting a prostate cancer related biomarker, comprising contacting the diluted sample with a modulating agent selected from a group consisting of sodium, 3-hydroxy-4-[(2-hydroxynaphthalen-1-yl)diazenyl]naphthalene-1-sulfonate, sodium, 3-hydroxy-4-[(1-hydroxynaphthalen-2-yl)diazenyl]-7-nitronaphthalene-1-sulfonate, triisopropylsilane, and iron(III) chloride, and a luminescent label to obtain a measurement sample. Then, the measurement sample is incubated for a period of time and excited thereafter. Time-resolved luminescence signal of the label in the measurement sample is measured, leading to an increased likelihood of prostate cancer of the human subject if the luminescence signal is at least 50 % higher than for a control sample from a human subject without prostate cancer. 本公开涉及用于检测前列腺癌相关生物标志物的方法，包括将经稀释样品与调节剂和发光标签接触以获得测量样品，所述调节剂选自由钠；3-羟基-4-[(2-羟基萘-1-基)二氮烯基]萘-1-磺酸酯、钠；3-羟基-4-[(1-羟基萘-2-基)二氮烯基]-7-硝基萘-1-磺酸酯、三异丙基硅烷，和氯化铁(III)组成的组。然后，将测量样品孵育一段时间，并随后进行激发。测量所述测量样品中所述标</description><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>PHYSICS</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDByVPB1DfHwd1Fw8w9ScHENcXUO8fRzV3BUCAjyDw5xDHFVcHb0c3YNUnDy9Pd1DPJ2DeJhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfHOfoaGxpYWJuZGBo7GxKgBAEspJno</recordid><startdate>20220128</startdate><enddate>20220128</enddate><creator>PAAVILAINEN SUSANNA</creator><creator>KULPAKKO JANNE</creator><creator>VEPSALAINEN JOUKO</creator><scope>EVB</scope></search><sort><creationdate>20220128</creationdate><title>A METHOD FOR DETECTING A PROSTATE CANCER BIOMARKER</title><author>PAAVILAINEN SUSANNA ; KULPAKKO JANNE ; VEPSALAINEN JOUKO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN113984720A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>PHYSICS</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>PAAVILAINEN SUSANNA</creatorcontrib><creatorcontrib>KULPAKKO JANNE</creatorcontrib><creatorcontrib>VEPSALAINEN JOUKO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PAAVILAINEN SUSANNA</au><au>KULPAKKO JANNE</au><au>VEPSALAINEN JOUKO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>A METHOD FOR DETECTING A PROSTATE CANCER BIOMARKER</title><date>2022-01-28</date><risdate>2022</risdate><abstract>The present disclosure relates to a method for detecting a prostate cancer related biomarker, comprising contacting the diluted sample with a modulating agent selected from a group consisting of sodium, 3-hydroxy-4-[(2-hydroxynaphthalen-1-yl)diazenyl]naphthalene-1-sulfonate, sodium, 3-hydroxy-4-[(1-hydroxynaphthalen-2-yl)diazenyl]-7-nitronaphthalene-1-sulfonate, triisopropylsilane, and iron(III) chloride, and a luminescent label to obtain a measurement sample. Then, the measurement sample is incubated for a period of time and excited thereafter. Time-resolved luminescence signal of the label in the measurement sample is measured, leading to an increased likelihood of prostate cancer of the human subject if the luminescence signal is at least 50 % higher than for a control sample from a human subject without prostate cancer. 本公开涉及用于检测前列腺癌相关生物标志物的方法，包括将经稀释样品与调节剂和发光标签接触以获得测量样品，所述调节剂选自由钠；3-羟基-4-[(2-羟基萘-1-基)二氮烯基]萘-1-磺酸酯、钠；3-羟基-4-[(1-羟基萘-2-基)二氮烯基]-7-硝基萘-1-磺酸酯、三异丙基硅烷，和氯化铁(III)组成的组。然后，将测量样品孵育一段时间，并随后进行激发。测量所述测量样品中所述标</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language chi ; eng
recordid cdi_epo_espacenet_CN113984720A
source esp@cenet
subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title A METHOD FOR DETECTING A PROSTATE CANCER BIOMARKER
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T14%3A49%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=PAAVILAINEN%20SUSANNA&rft.date=2022-01-28&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN113984720A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true