Monofluoroiodoacetone compound as well as preparation method and application thereof

The invention relates to a monofluoroiodoacetone compound as well as a preparation method and application thereof, wherein the monofluoroiodoacetone compound has the following structural formula shown in the specification, wherein R1 is one of phenyl, condensed ring, substituted phenyl, alkyl or heterocyclic ring. The preparation method comprises the steps: mixing a compound represented by a formula (1), lithium iodide and a halogenating reagent in an organic solvent, stirring and reacting for 10-40 minutes in an ice bath, then adding triethylamine, reacting at the temperature of -20 DEG C to 40 DEG C, and separating and purifying to obtain the monofluoroiodoacetone compound. Compared with the prior art, the method has the advantages of high reaction efficiency, short reaction time, high yield, mild reaction conditions and the like, can be used as a monofluoroalkylation reagent and can also be used as a general building block for various organic synthesis reactions, so that the method has a quite good applica