NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR TREATMENT OF DISEASES
The present invention discloses compounds according to Formula (I), wherein R1a, R1b, R1c, R2a, W1, W2, X1, X2, X3, Y, and Z are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment usin...
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| creator | DUTHION BERANGER ALVEY LUKE TIRERA AMYNATA BONNATERRE FLORENCE BUCHER DENIS JARY HELENE M DESROY NICOLAS PEIXOTO CHRISTOPHE TEMAL-LAIB TAOUES |
| description | The present invention discloses compounds according to Formula (I), wherein R1a, R1b, R1c, R2a, W1, W2, X1, X2, X3, Y, and Z are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, fibrotic diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformation, diseases involving impairment of bone turnover, diseases associated with hypersecretion of IL-6, diseases associated with hypersecretion of TNF alpha, interferons, IL-12 and/or IL-23, respiratory diseases, endocrine and/or metabolic diseases, cardiovascular diseases, dermatological diseases, and/or abnormal angiogenesis associated diseases by administering the compound of the invention.
本发明公开了式(I)的化合物，其中R1a、R1b、R1c、R2a、W1、W2、X1、X2、X3、Y和Z如本 |
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本发明公开了式(I)的化合物，其中R1a、R1b、R1c、R2a、W1、W2、X1、X2、X3、Y和Z如本</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220111&DB=EPODOC&CC=CN&NR=113924146A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220111&DB=EPODOC&CC=CN&NR=113924146A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DUTHION BERANGER</creatorcontrib><creatorcontrib>ALVEY LUKE</creatorcontrib><creatorcontrib>TIRERA AMYNATA</creatorcontrib><creatorcontrib>BONNATERRE FLORENCE</creatorcontrib><creatorcontrib>BUCHER DENIS</creatorcontrib><creatorcontrib>JARY HELENE M</creatorcontrib><creatorcontrib>DESROY NICOLAS</creatorcontrib><creatorcontrib>PEIXOTO CHRISTOPHE</creatorcontrib><creatorcontrib>TEMAL-LAIB TAOUES</creatorcontrib><title>NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR TREATMENT OF DISEASES</title><description>The present invention discloses compounds according to Formula (I), wherein R1a, R1b, R1c, R2a, W1, W2, X1, X2, X3, Y, and Z are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, fibrotic diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformation, diseases involving impairment of bone turnover, diseases associated with hypersecretion of IL-6, diseases associated with hypersecretion of TNF alpha, interferons, IL-12 and/or IL-23, respiratory diseases, endocrine and/or metabolic diseases, cardiovascular diseases, dermatological diseases, and/or abnormal angiogenesis associated diseases by administering the compound of the invention.
本发明公开了式(I)的化合物，其中R1a、R1b、R1c、R2a、W1、W2、X1、X2、X3、Y和Z如本</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNikEKwjAQAHPxIOof1gd4iC2CxyXZkIDZ1GTrtRSJJ9FC_T966AM8DczMWl053egCJsUu9WwLIFvoPOaIhnoJBpdYgoTEBcRTpuTApQySCSUSC_yEDYWwUNmq1WN8znW3cKP2jsT4Q53eQ52n8V5f9TMY1ro5H1vdnrD55_kCzREvnQ</recordid><startdate>20220111</startdate><enddate>20220111</enddate><creator>DUTHION BERANGER</creator><creator>ALVEY LUKE</creator><creator>TIRERA AMYNATA</creator><creator>BONNATERRE FLORENCE</creator><creator>BUCHER DENIS</creator><creator>JARY HELENE M</creator><creator>DESROY NICOLAS</creator><creator>PEIXOTO CHRISTOPHE</creator><creator>TEMAL-LAIB TAOUES</creator><scope>EVB</scope></search><sort><creationdate>20220111</creationdate><title>NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR TREATMENT OF DISEASES</title><author>DUTHION BERANGER ; ALVEY LUKE ; TIRERA AMYNATA ; BONNATERRE FLORENCE ; BUCHER DENIS ; JARY HELENE M ; DESROY NICOLAS ; PEIXOTO CHRISTOPHE ; TEMAL-LAIB TAOUES</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN113924146A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DUTHION BERANGER</creatorcontrib><creatorcontrib>ALVEY LUKE</creatorcontrib><creatorcontrib>TIRERA AMYNATA</creatorcontrib><creatorcontrib>BONNATERRE FLORENCE</creatorcontrib><creatorcontrib>BUCHER DENIS</creatorcontrib><creatorcontrib>JARY HELENE M</creatorcontrib><creatorcontrib>DESROY NICOLAS</creatorcontrib><creatorcontrib>PEIXOTO CHRISTOPHE</creatorcontrib><creatorcontrib>TEMAL-LAIB TAOUES</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DUTHION BERANGER</au><au>ALVEY LUKE</au><au>TIRERA AMYNATA</au><au>BONNATERRE FLORENCE</au><au>BUCHER DENIS</au><au>JARY HELENE M</au><au>DESROY NICOLAS</au><au>PEIXOTO CHRISTOPHE</au><au>TEMAL-LAIB TAOUES</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR TREATMENT OF DISEASES</title><date>2022-01-11</date><risdate>2022</risdate><abstract>The present invention discloses compounds according to Formula (I), wherein R1a, R1b, R1c, R2a, W1, W2, X1, X2, X3, Y, and Z are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, fibrotic diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformation, diseases involving impairment of bone turnover, diseases associated with hypersecretion of IL-6, diseases associated with hypersecretion of TNF alpha, interferons, IL-12 and/or IL-23, respiratory diseases, endocrine and/or metabolic diseases, cardiovascular diseases, dermatological diseases, and/or abnormal angiogenesis associated diseases by administering the compound of the invention.
本发明公开了式(I)的化合物，其中R1a、R1b、R1c、R2a、W1、W2、X1、X2、X3、Y和Z如本</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR TREATMENT OF DISEASES |
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