AAV VECTOR TREATMENT METHODS FOR LATE INFANTILE NEURONAL CEROID LIPOFUSCINOSIS TYPE 2
Disclosed herein are methods for treating a primate in need of tripeptidyl peptidase 1 (TPP1), comprising (a) providing a recombinant adeno-associated virus (AAV) vector comprising a nucleic acid encoding TPP1; and (b) administering an amount of the recombinant AAV vector to the central nervous syst...
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| creator | ANDERSON DAVID WILLIAM TOTO MARYANN DASEN SUE E I |
| description | Disclosed herein are methods for treating a primate in need of tripeptidyl peptidase 1 (TPP1), comprising (a) providing a recombinant adeno-associated virus (AAV) vector comprising a nucleic acid encoding TPP1; and (b) administering an amount of the recombinant AAV vector to the central nervous system (CNS) of the primate, wherein the TPP1 is expressed in the primate.
本文公开了用于治疗需要三肽基肽酶1(TPP1)的灵长类动物的方法，该方法包括(a)提供包含编码TPP1的核酸的重组腺相关病毒(AAV)载体；以及(b)向灵长类动物的中枢神经系统(CNS)施用一定量的重组AAV载体，其中TPP1在灵长类动物中表达。 |
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本文公开了用于治疗需要三肽基肽酶1(TPP1)的灵长类动物的方法，该方法包括(a)提供包含编码TPP1的核酸的重组腺相关病毒(AAV)载体；以及(b)向灵长类动物的中枢神经系统(CNS)施用一定量的重组AAV载体，其中TPP1在灵长类动物中表达。</description><language>chi ; eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220104&DB=EPODOC&CC=CN&NR=113891712A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220104&DB=EPODOC&CC=CN&NR=113891712A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ANDERSON DAVID WILLIAM</creatorcontrib><creatorcontrib>TOTO MARYANN</creatorcontrib><creatorcontrib>DASEN SUE E I</creatorcontrib><title>AAV VECTOR TREATMENT METHODS FOR LATE INFANTILE NEURONAL CEROID LIPOFUSCINOSIS TYPE 2</title><description>Disclosed herein are methods for treating a primate in need of tripeptidyl peptidase 1 (TPP1), comprising (a) providing a recombinant adeno-associated virus (AAV) vector comprising a nucleic acid encoding TPP1; and (b) administering an amount of the recombinant AAV vector to the central nervous system (CNS) of the primate, wherein the TPP1 is expressed in the primate.
本文公开了用于治疗需要三肽基肽酶1(TPP1)的灵长类动物的方法，该方法包括(a)提供包含编码TPP1的核酸的重组腺相关病毒(AAV)载体；以及(b)向灵长类动物的中枢神经系统(CNS)施用一定量的重组AAV载体，其中TPP1在灵长类动物中表达。</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQgOEsDqK-w_kADmkHdTzSCw2kl5JcCp1KkTiJFur7o4MP4PTDx79VGXGAgYyECBIJpSMW6Eja0CSwX_UoBI4tsjhPwJRjYPRgKAbXgHd9sDkZxyG5BDL2BNVebe7zYy2HX3fqaElMeyrLayrrMt_Ks7wnw1rXl6s-6wrrf54Pa00wgA</recordid><startdate>20220104</startdate><enddate>20220104</enddate><creator>ANDERSON DAVID WILLIAM</creator><creator>TOTO MARYANN</creator><creator>DASEN SUE E I</creator><scope>EVB</scope></search><sort><creationdate>20220104</creationdate><title>AAV VECTOR TREATMENT METHODS FOR LATE INFANTILE NEURONAL CEROID LIPOFUSCINOSIS TYPE 2</title><author>ANDERSON DAVID WILLIAM ; TOTO MARYANN ; DASEN SUE E I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN113891712A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ANDERSON DAVID WILLIAM</creatorcontrib><creatorcontrib>TOTO MARYANN</creatorcontrib><creatorcontrib>DASEN SUE E I</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ANDERSON DAVID WILLIAM</au><au>TOTO MARYANN</au><au>DASEN SUE E I</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>AAV VECTOR TREATMENT METHODS FOR LATE INFANTILE NEURONAL CEROID LIPOFUSCINOSIS TYPE 2</title><date>2022-01-04</date><risdate>2022</risdate><abstract>Disclosed herein are methods for treating a primate in need of tripeptidyl peptidase 1 (TPP1), comprising (a) providing a recombinant adeno-associated virus (AAV) vector comprising a nucleic acid encoding TPP1; and (b) administering an amount of the recombinant AAV vector to the central nervous system (CNS) of the primate, wherein the TPP1 is expressed in the primate.
本文公开了用于治疗需要三肽基肽酶1(TPP1)的灵长类动物的方法，该方法包括(a)提供包含编码TPP1的核酸的重组腺相关病毒(AAV)载体；以及(b)向灵长类动物的中枢神经系统(CNS)施用一定量的重组AAV载体，其中TPP1在灵长类动物中表达。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | AAV VECTOR TREATMENT METHODS FOR LATE INFANTILE NEURONAL CEROID LIPOFUSCINOSIS TYPE 2 |
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