Tofacitinib citrate intermediate impurity and preparation method thereof

The invention provides a preparation method of a tofacitinib citrate intermediate impurity (compound I), which comprises the following steps: adding sodium hydride in batches at 0-10 DEG C, heating the material to room temperature after adding, and then slowly heating the material to 50-70 DEG C for...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	JIE YUANPING, LI HENGTAO, WU XIHAN, DENG LUJIANG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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