Application of neojusticidin B in preparation of blood fat reducing drug

The invention provides an application of neojusticidin B in preparation of a blood fat reducing drug. The neojusticidin B has the effects of reducing lipid absorption and operation and accelerating lipid clearance by up-regulating the expression of apolipoprotein A-II and apolipoprotein C-II and down-regulating the expression of glycoprotein IIIb; and the anticoagulant effect is generated by down-regulating the expression of a blood coagulation factor X, the anti-platelet aggregation effect is generated by down-regulating the expression of fibrinogen, and the antithrombotic effect is realized through anticoagulation and anti-platelet aggregation. The neojusticidin B is novel in blood fat reducing action mechanism, provides a new scheme for treatment of hyperlipidemia diseases, and particularly provides a new scheme for clinical treatment of thrombotic diseases further caused by atherosclerosis caused by hyperlipidemia. 本发明提供了新爵床脂定B在制备降血脂药物中的应用。本发明的新爵床脂定B通过上调载脂蛋白A-Ⅱ、载脂蛋白C-II的表达，下调糖蛋白Ⅲb的表达，产生降低脂质吸收和运转、加速脂质清除的作用