Synthesis method of compound with phosphine chirality and axial chirality
The invention relates to a synthesis method of a compound with phosphine chirality and axial chirality. The method comprises the following steps: in an organic solvent system, synthesizing by taking a diaryl phosphine oxide compound and diaryl alkyne as basic raw materials under the effect of an iri...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Patent |
| Sprache: | chi ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | DUAN WEILIANG ZHANG CHAOWEI |
| description | The invention relates to a synthesis method of a compound with phosphine chirality and axial chirality. The method comprises the following steps: in an organic solvent system, synthesizing by taking a diaryl phosphine oxide compound and diaryl alkyne as basic raw materials under the effect of an iridium catalyst, an oxidizing agent and a chiral amide ligand, and carrying out post-treatment on a reaction solution to obtain the compound with phosphine chirality and axial chirality. The diaryl phosphine oxide used in the reaction is simple and easy to synthesize, the universality of the substrate is better, the reaction operation is simple and convenient, and the efficiency is high. Synthesis of a ligand is relatively convenient, the ligand is combined with metal in the reaction, and the C-H bond on a benzene ring is selectively activated under the guidance of phosphine oxide of the substrate, so that the carbon-hydrogen bond activation arylation reaction among molecules is realized, and the compound with phosph |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN113735899A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN113735899A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN113735899A3</originalsourceid><addsrcrecordid>eNrjZPAMrswryUgtzixWyE0tychPUchPU0jOzy3IL81LUSjPLMlQKMjILy7IyMxLVUjOyCxKzMksqVRIBEomVmQm5iDEeBhY0xJzilN5oTQ3g6Kba4izh25qQX58anFBYnJqXmpJvLOfoaGxubGphaWlozExagAo2zVP</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Synthesis method of compound with phosphine chirality and axial chirality</title><source>esp@cenet</source><creator>DUAN WEILIANG ; ZHANG CHAOWEI</creator><creatorcontrib>DUAN WEILIANG ; ZHANG CHAOWEI</creatorcontrib><description>The invention relates to a synthesis method of a compound with phosphine chirality and axial chirality. The method comprises the following steps: in an organic solvent system, synthesizing by taking a diaryl phosphine oxide compound and diaryl alkyne as basic raw materials under the effect of an iridium catalyst, an oxidizing agent and a chiral amide ligand, and carrying out post-treatment on a reaction solution to obtain the compound with phosphine chirality and axial chirality. The diaryl phosphine oxide used in the reaction is simple and easy to synthesize, the universality of the substrate is better, the reaction operation is simple and convenient, and the efficiency is high. Synthesis of a ligand is relatively convenient, the ligand is combined with metal in the reaction, and the C-H bond on a benzene ring is selectively activated under the guidance of phosphine oxide of the substrate, so that the carbon-hydrogen bond activation arylation reaction among molecules is realized, and the compound with phosph</description><language>chi ; eng</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; THEIR RELEVANT APPARATUS ; TRANSPORTING</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211203&DB=EPODOC&CC=CN&NR=113735899A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211203&DB=EPODOC&CC=CN&NR=113735899A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DUAN WEILIANG</creatorcontrib><creatorcontrib>ZHANG CHAOWEI</creatorcontrib><title>Synthesis method of compound with phosphine chirality and axial chirality</title><description>The invention relates to a synthesis method of a compound with phosphine chirality and axial chirality. The method comprises the following steps: in an organic solvent system, synthesizing by taking a diaryl phosphine oxide compound and diaryl alkyne as basic raw materials under the effect of an iridium catalyst, an oxidizing agent and a chiral amide ligand, and carrying out post-treatment on a reaction solution to obtain the compound with phosphine chirality and axial chirality. The diaryl phosphine oxide used in the reaction is simple and easy to synthesize, the universality of the substrate is better, the reaction operation is simple and convenient, and the efficiency is high. Synthesis of a ligand is relatively convenient, the ligand is combined with metal in the reaction, and the C-H bond on a benzene ring is selectively activated under the guidance of phosphine oxide of the substrate, so that the carbon-hydrogen bond activation arylation reaction among molecules is realized, and the compound with phosph</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>THEIR RELEVANT APPARATUS</subject><subject>TRANSPORTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPAMrswryUgtzixWyE0tychPUchPU0jOzy3IL81LUSjPLMlQKMjILy7IyMxLVUjOyCxKzMksqVRIBEomVmQm5iDEeBhY0xJzilN5oTQ3g6Kba4izh25qQX58anFBYnJqXmpJvLOfoaGxubGphaWlozExagAo2zVP</recordid><startdate>20211203</startdate><enddate>20211203</enddate><creator>DUAN WEILIANG</creator><creator>ZHANG CHAOWEI</creator><scope>EVB</scope></search><sort><creationdate>20211203</creationdate><title>Synthesis method of compound with phosphine chirality and axial chirality</title><author>DUAN WEILIANG ; ZHANG CHAOWEI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN113735899A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2021</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>THEIR RELEVANT APPARATUS</topic><topic>TRANSPORTING</topic><toplevel>online_resources</toplevel><creatorcontrib>DUAN WEILIANG</creatorcontrib><creatorcontrib>ZHANG CHAOWEI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DUAN WEILIANG</au><au>ZHANG CHAOWEI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Synthesis method of compound with phosphine chirality and axial chirality</title><date>2021-12-03</date><risdate>2021</risdate><abstract>The invention relates to a synthesis method of a compound with phosphine chirality and axial chirality. The method comprises the following steps: in an organic solvent system, synthesizing by taking a diaryl phosphine oxide compound and diaryl alkyne as basic raw materials under the effect of an iridium catalyst, an oxidizing agent and a chiral amide ligand, and carrying out post-treatment on a reaction solution to obtain the compound with phosphine chirality and axial chirality. The diaryl phosphine oxide used in the reaction is simple and easy to synthesize, the universality of the substrate is better, the reaction operation is simple and convenient, and the efficiency is high. Synthesis of a ligand is relatively convenient, the ligand is combined with metal in the reaction, and the C-H bond on a benzene ring is selectively activated under the guidance of phosphine oxide of the substrate, so that the carbon-hydrogen bond activation arylation reaction among molecules is realized, and the compound with phosph</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | chi ; eng |
| recordid | cdi_epo_espacenet_CN113735899A |
| source | esp@cenet |
| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL THEIR RELEVANT APPARATUS TRANSPORTING |
| title | Synthesis method of compound with phosphine chirality and axial chirality |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T19%3A23%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=DUAN%20WEILIANG&rft.date=2021-12-03&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN113735899A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |