Macrophage 1 in preparation of medicine for treating pulmonary arterial hypertension and application of macrophage 1
The invention discloses an application of macrophage 1 in preparation of a medicine for treating pulmonary arterial hypertension, through the application, a new pulmonary arterial hypertension treatment scheme can be provided, and the macrophage Maresin 1 can reverse pulmonary arterial hypertension...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses an application of macrophage 1 in preparation of a medicine for treating pulmonary arterial hypertension, through the application, a new pulmonary arterial hypertension treatment scheme can be provided, and the macrophage Maresin 1 can reverse pulmonary arterial hypertension and can improve right heart dysfunction, and vascular remodeling is improved by inhibiting transformation from endothelial cells to interstitial cells and promoting apoptosis of pulmonary vascular smooth muscle cells.
本发明公开了巨噬素1在制备治疗肺动脉高压药物中的应用,通过该应用能够提供一种新的肺动脉高压治疗方案,巨噬素Maresin1可逆转肺动脉高压,改善右心功能障碍,通过抑制内皮细胞向间质细胞转化和促进肺血管平滑肌细胞的凋亡而改善血管重塑来实现。 |
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