Lipid-lowering medicinal composition

The invention discloses a lipid-lowering medicinal composition. The lipid-lowering medicinal composition is prepared from the components in percentage by mass: 10%-60% of justicidin B, 4%-60% of stephania sinica diels methyl ether and 3%-50% of new justicidin B. According to the lipid-lowering medic...

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Bibliographische Detailangaben
Hauptverfasser: LU YI, LIU BO, WU SONGTAO, HONG ZONGCHAO, WU HEZHEN, YANG YANFANG, AI ZHONGZHU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a lipid-lowering medicinal composition. The lipid-lowering medicinal composition is prepared from the components in percentage by mass: 10%-60% of justicidin B, 4%-60% of stephania sinica diels methyl ether and 3%-50% of new justicidin B. According to the lipid-lowering medicinal composition, the expression of apolipoprotein A-II and apolipoprotein C-II is up-regulated, so that the effect of accelerating lipid transfer negative regulation is generated; and the anticoagulant effect is generated by down-regulating expression of protein AMBP and prothrombin, the anti-platelet aggregation effect is generated by down-regulating expression of fibrinogen, and the antithrombotic effect is achieved through anticoagulation and anti-platelet aggregation. The lipid-lowering medicinal composition is novel in action mechanism of reducing blood fat, resisting inflammation and inhibiting thrombus, and can be used for preventing and treating the whole cardiovascular disease course. The lipid-lowering m