Hydrocarbyl pyrrole aldehyde derivative as well as preparation method and application thereof

The invention discloses a hydrocarbyl pyrrole aldehyde derivative and a preparation method and application thereof, the structural formula of the hydrocarbyl pyrrole aldehyde derivative is shown in the specification, and the hydrocarbyl pyrrole aldehyde derivative has a relatively good inhibition ef...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: XU LI, LUO LIANZHONG, CHEN DAN, YANG CAIJUAN, LIN YUNYONG, ZHANG GANG, YANG RONG, WANG XUNMING
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention discloses a hydrocarbyl pyrrole aldehyde derivative and a preparation method and application thereof, the structural formula of the hydrocarbyl pyrrole aldehyde derivative is shown in the specification, and the hydrocarbyl pyrrole aldehyde derivative has a relatively good inhibition effect on mycobacterium tuberculosis H37Rv, has relatively low toxicity to normal cells, and can be used as a novel candidate drug for treating pulmonary tuberculosis. 本发明公开了一种烃基吡咯醛衍生物及其制备方法和应用,其结构式为本发明对结核分枝杆菌H37Rv具有较好的抑制效果,且对正常细胞的毒性都较低,可以作为治疗肺结核的新型候选药物。