BIPARATOPIC AND MULTIPARATOPIC ANTIBODIES WITH COMMON LIGHT CHAIN AND METHOD OF USE

The present invention relates to bispecific or multi-specific antibody molecules with two or more paratopes. At least one paratope is Fv or scFv, while the other paratope is in a mono-valent or bivalent Fab. These novel molecules also have an Fc moiety that allows extended half-life in vivo. 本发明涉及具有...

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Bibliographische Detailangaben
Hauptverfasser: ZHU XIAODONG, XIAO SHOUHUA
Format: Patent
Sprache:chi ; eng
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