Absorbable hydrogel composition for promoting wound healing and preparation method and application thereof

Absorbable hydrogel composition for promoting wound healing and preparation method and application thereof

The invention relates to an absorbable hydrogel composition for promoting wound healing and a preparation method and application thereof, and belongs to the technical field of medical auxiliary materials. The hydrogel composition is prepared from, by mass, 18000-22000 parts of PCEC copolymer, 1-2 pa...

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Hauptverfasser: LIU QUANBIN, CUI FENGMEI
Format: Patent
Sprache:chi ; eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator LIU QUANBIN
CUI FENGMEI
description The invention relates to an absorbable hydrogel composition for promoting wound healing and a preparation method and application thereof, and belongs to the technical field of medical auxiliary materials. The hydrogel composition is prepared from, by mass, 18000-22000 parts of PCEC copolymer, 1-2 parts of loureirin A and 1-3 parts of collagen. The PCEC copolymer is formed by dissolving a triblock polymer synthesized through a ring-opening polymerization method, hydrogel is free of toxicity and has good biocompatibility, meanwhile, hydrogen bonds or electrostatic acting force is formed between the hydrogel and encapsulated medicine micromolecules, and therefore the hydrogel can be well applied to in-vivo and in-vitro medicine and micromolecule conveying. A PCEC carrier has a good slow release effect on the loureirin A loaded into the PCEC carrier, medicine quick release is avoided, and the reason is that PCECA can promote wound healing. The PCECAplus has good physical and chemical properties, can carry medicin
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The hydrogel composition is prepared from, by mass, 18000-22000 parts of PCEC copolymer, 1-2 parts of loureirin A and 1-3 parts of collagen. The PCEC copolymer is formed by dissolving a triblock polymer synthesized through a ring-opening polymerization method, hydrogel is free of toxicity and has good biocompatibility, meanwhile, hydrogen bonds or electrostatic acting force is formed between the hydrogel and encapsulated medicine micromolecules, and therefore the hydrogel can be well applied to in-vivo and in-vitro medicine and micromolecule conveying. A PCEC carrier has a good slow release effect on the loureirin A loaded into the PCEC carrier, medicine quick release is avoided, and the reason is that PCECA can promote wound healing. 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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Absorbable hydrogel composition for promoting wound healing and preparation method and application thereof
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