Application of inactivated lactic acid bacteria compound in preparation of product for treating and/or preventing diabetes
The invention provides application of an inactivated lactic acid bacteria compound in preparation of a product for treating and/or preventing diabetes, and belongs to the technical field of blood sugar reduction. Lactobacillus plantarum CICC 24202 and lactobacillus brevis YM 1301 are mixed and inact...
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| creator | HUANG CHUNYING WEI QIANQIAN XUE NAN ZHANG BAOSHAN DANG YUANJIE ZHOU RONGCUN WAN JUAN ZHOU YANGJING GAO JINGRU LI FARONG |
| description | The invention provides application of an inactivated lactic acid bacteria compound in preparation of a product for treating and/or preventing diabetes, and belongs to the technical field of blood sugar reduction. Lactobacillus plantarum CICC 24202 and lactobacillus brevis YM 1301 are mixed and inactivated, and in a type 2 diabetes model induced by combination of high-fat feed and multiple times of small-dose streptozotocin, the improvement degree of an inactivated bacteria group on type 2 diabetes can reach the level of a viable bacteria group; and the food intake and water intake of type 2 diabetes model mice can be reduced, the body weight of the mice can be increased to a certain extent, blood sugar can be effectively reduced, insulin sensitivity can be improved, and insulin resistance can be improved. Moreover, the inactivated bacteria obviously reduce fat accumulation of the mice with type 2 diabetes, improve renal dysfunction caused by diabetes to a certain extent, and can be applied to preparation of a |
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| subjects | FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES |
| title | Application of inactivated lactic acid bacteria compound in preparation of product for treating and/or preventing diabetes |
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