Related-gene detection kit for guiding anxiety disorder medication and application

The invention discloses a related-gene detection kit for guiding anxiety disorder medication and application. The related-gene detection kit comprises specific primers and probes for detecting a rs776746 site of a CYP3A5 gene and a rs1902023 site of a UGT2B15 gene. The detection kit is good in detec...

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Hauptverfasser: SUN XIAOXIAO, XUE BINYU, ZHANG YUE, XUE XIA, ZHAN MINNING, FENG SHUAISHENG, XU HONG'EN, QIN YAPING, LIU HAIFANG, GUO JIANCHENG, ZHU DANDAN, SHI JIANXIANG, LIU DANHUA
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creator SUN XIAOXIAO
XUE BINYU
ZHANG YUE
XUE XIA
ZHAN MINNING
FENG SHUAISHENG
XU HONG'EN
QIN YAPING
LIU HAIFANG
GUO JIANCHENG
ZHU DANDAN
SHI JIANXIANG
LIU DANHUA
description The invention discloses a related-gene detection kit for guiding anxiety disorder medication and application. The related-gene detection kit comprises specific primers and probes for detecting a rs776746 site of a CYP3A5 gene and a rs1902023 site of a UGT2B15 gene. The detection kit is good in detection specificity, high in sensitivity, short in consumed time and low in cost, an ARMS primer design is adopted, the primers are mismatched with bases to improve the specificity of amplification, the sensitivity is high, and the rs776746 site of the human CYP3A5 gene and the rs1902023 site of the UGT2B15 gene can be accurately typed with the minimum initial amount of 10ngDNA; the PCR only needs less than 1 hour to complete the amplification reaction, the consumed time is short, and rapid detection can be carried out clinically; and required reagent consumables are all clinically common reagents, so that the cost is low, and the clinical popularization is convenient. 本发明公开一种用于指导焦虑症用药的相关基因检测试剂盒及应用,其包括检测CYP3A5基因rs7767
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title Related-gene detection kit for guiding anxiety disorder medication and application
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