Rapid cell classification and quantification method based on coffee ring

The invention discloses a rapid cell classification and quantification method based on a coffee ring and belongs to the field of cell detection. The key point of the invention is to provide an LIBS signal acquisition method of a cell suspension coffee ring, which mainly comprises the following steps...

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Bibliographische Detailangaben
Hauptverfasser: LIN QINGYU, YIN PENGKUN, DUAN YIXIANG, KANG MENGKE
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a rapid cell classification and quantification method based on a coffee ring and belongs to the field of cell detection. The key point of the invention is to provide an LIBS signal acquisition method of a cell suspension coffee ring, which mainly comprises the following steps of dropwise adding a cell suspension to a monocrystalline silicon wafer, naturally drying to form a coffee ring, and then carrying out LIBS signal acquisition on endogenous characteristic elements of cells in a coffee ring area. The invention further provides a method for constructing the cell characteristic annular imprinting fingerprint element atlas database and the corresponding cell characteristic annular imprinting fingerprint element atlas database. The invention also provides a cell classification method which is used for realizing cell classification by comparing the sample annular mark fingerprint element atlas with the atlas database. The invention also provides a cell quantification method based on the