Preparation method of targeted drug BLU-667

The invention discloses a preparation method of a targeted drug BLU-667. The preparation method comprises the following steps: firstly, carrying out BOC protection on amino of 2-chloro-4-methyl-6-aminopyrimidine, carrying out carbon-carbon coupling on the obtained intermediate 1 and an iodo compound...

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Bibliographische Detailangaben
Hauptverfasser: LIU YADONG, WANG JINBING, CHEN QIANGQIANG, NING SHANG'EN, ZHANG JINGSHEN, ZHOU JIAN
Format: Patent
Sprache:chi ; eng
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