Coconut oil nanosphere and preparation method thereof

The invention provides a coconut oil nanosphere and a preparation method thereof. The preparation method comprises the following steps of: (1) mixing deoxycholate and soybean lecithin according to a mass ratio of 1: (2-4), and then adding an organic solvent and coconut oil to obtain a mixture, wherein the mass-volume ratio g/ml of the soybean lecithin to the coconut oil is 4: (0.5-1.5); and (2) carrying out ultrasonic dispersion on the mixture obtained in the step (1), carrying out rotary evaporation, then adding a phosphate buffer salt solution, and carrying out hydration at a temperature of 55-65 DEG C for 20-40 min to obtain the coconut oil nanosphere. The coconut oil nanosphere prepared by the preparation method provided by the invention is high in encapsulation efficiency and stable in structure. 本发明提供一种椰子油纳米球及其制备方法，该制备方法包括以下步骤：(1)将脱氧胆盐和大豆卵磷脂按质量比1：2-4混合，再加入有机溶剂和椰子油，得混合物，所述大豆卵磷脂和椰子油的质量体积比g/ml为4：0.5-1.5；(2)将步骤(1)混合物超声分散，旋蒸后，再加入磷酸缓冲盐溶液，在55-65℃温度下水化20-40min，得到椰子油纳米球。本发明制得椰子油纳米球包封率高，而且结构稳定。