Synthesis method of semetinib

The invention relates to a synthesis method of simetinib. According to the method, diethoxymethane is creatively adopted as a ring closing reactant, and two-step reaction of ring closing reaction and methylation is combined into one step, so the yield is very high, and the number of reaction steps i...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	FAN ZHAOZE, LIU SHAOQUN, CHEN LONG, HU RENJUN, DUN WEI, YU YANPING, LI XURONG, HUANG XIANGQUAN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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