Antibacterial peptide and application thereof
The invention discloses an antibacterial peptide, the amino acid sequence of which is SEQ ID NO: 1, and also provides an antibacterial peptide with specific targeting, and related functional verification is carried out. The invention further provides application of the antibacterial peptide in prepa...
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| creator | RU SHAOGUO TAN RONG CUI PENGFEI XIONG JIUQIANG |
| description | The invention discloses an antibacterial peptide, the amino acid sequence of which is SEQ ID NO: 1, and also provides an antibacterial peptide with specific targeting, and related functional verification is carried out. The invention further provides application of the antibacterial peptide in preparation of drugs or feed additives for preventing and treating bacterial infection. The antibacterial peptide provided by the invention can kill gram-negative bacteria and gram-positive bacteria by causing mechanisms such as cell membrane destruction, but has no toxicity to mammalian cells.
本方法公开了一种抗菌肽，其氨基酸序列为SEQ ID NO:1，同时，本发明还提供了具有特异靶向性的抗菌肽，并进行了相关功能验证。本发明进一步提供了抗菌肽在制备用于防治细菌感染的药物或饲料添加剂中的应用。本发明提供的抗菌肽能够通过引起细胞膜破坏等机制杀死革兰氏阴性菌和革兰氏阳性菌，但却对哺乳动物细胞没有毒性。 |
| format | Patent |
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本方法公开了一种抗菌肽，其氨基酸序列为SEQ ID NO:1，同时，本发明还提供了具有特异靶向性的抗菌肽，并进行了相关功能验证。本发明进一步提供了抗菌肽在制备用于防治细菌感染的药物或饲料添加剂中的应用。本发明提供的抗菌肽能够通过引起细胞膜破坏等机制杀死革兰氏阴性菌和革兰氏阳性菌，但却对哺乳动物细胞没有毒性。</description><language>chi ; eng</language><subject>CHEMISTRY ; FODDER ; FOODS OR FOODSTUFFS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210430&DB=EPODOC&CC=CN&NR=112724202A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210430&DB=EPODOC&CC=CN&NR=112724202A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RU SHAOGUO</creatorcontrib><creatorcontrib>TAN RONG</creatorcontrib><creatorcontrib>CUI PENGFEI</creatorcontrib><creatorcontrib>XIONG JIUQIANG</creatorcontrib><title>Antibacterial peptide and application thereof</title><description>The invention discloses an antibacterial peptide, the amino acid sequence of which is SEQ ID NO: 1, and also provides an antibacterial peptide with specific targeting, and related functional verification is carried out. The invention further provides application of the antibacterial peptide in preparation of drugs or feed additives for preventing and treating bacterial infection. The antibacterial peptide provided by the invention can kill gram-negative bacteria and gram-positive bacteria by causing mechanisms such as cell membrane destruction, but has no toxicity to mammalian cells.
本方法公开了一种抗菌肽，其氨基酸序列为SEQ ID NO:1，同时，本发明还提供了具有特异靶向性的抗菌肽，并进行了相关功能验证。本发明进一步提供了抗菌肽在制备用于防治细菌感染的药物或饲料添加剂中的应用。本发明提供的抗菌肽能够通过引起细胞膜破坏等机制杀死革兰氏阴性菌和革兰氏阳性菌，但却对哺乳动物细胞没有毒性。</description><subject>CHEMISTRY</subject><subject>FODDER</subject><subject>FOODS OR FOODSTUFFS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNB1zCvJTEpMLkktykzMUShILSjJTElVSMxLUUgsKMjJTE4syczPUyjJSC1KzU_jYWBNS8wpTuWF0twMim6uIc4euqkF-fGpxQWJyal5qSXxzn6GhkbmRiZGBkaOxsSoAQDe-CpQ</recordid><startdate>20210430</startdate><enddate>20210430</enddate><creator>RU SHAOGUO</creator><creator>TAN RONG</creator><creator>CUI PENGFEI</creator><creator>XIONG JIUQIANG</creator><scope>EVB</scope></search><sort><creationdate>20210430</creationdate><title>Antibacterial peptide and application thereof</title><author>RU SHAOGUO ; TAN RONG ; CUI PENGFEI ; XIONG JIUQIANG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN112724202A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>FODDER</topic><topic>FOODS OR FOODSTUFFS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</topic><toplevel>online_resources</toplevel><creatorcontrib>RU SHAOGUO</creatorcontrib><creatorcontrib>TAN RONG</creatorcontrib><creatorcontrib>CUI PENGFEI</creatorcontrib><creatorcontrib>XIONG JIUQIANG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RU SHAOGUO</au><au>TAN RONG</au><au>CUI PENGFEI</au><au>XIONG JIUQIANG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Antibacterial peptide and application thereof</title><date>2021-04-30</date><risdate>2021</risdate><abstract>The invention discloses an antibacterial peptide, the amino acid sequence of which is SEQ ID NO: 1, and also provides an antibacterial peptide with specific targeting, and related functional verification is carried out. The invention further provides application of the antibacterial peptide in preparation of drugs or feed additives for preventing and treating bacterial infection. The antibacterial peptide provided by the invention can kill gram-negative bacteria and gram-positive bacteria by causing mechanisms such as cell membrane destruction, but has no toxicity to mammalian cells.
本方法公开了一种抗菌肽，其氨基酸序列为SEQ ID NO:1，同时，本发明还提供了具有特异靶向性的抗菌肽，并进行了相关功能验证。本发明进一步提供了抗菌肽在制备用于防治细菌感染的药物或饲料添加剂中的应用。本发明提供的抗菌肽能够通过引起细胞膜破坏等机制杀死革兰氏阴性菌和革兰氏阳性菌，但却对哺乳动物细胞没有毒性。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY FODDER FOODS OR FOODSTUFFS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES |
| title | Antibacterial peptide and application thereof |
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