Rapid-to-disintegrate vaginal soft capsule composition and preparation method thereof

Rapid-to-disintegrate vaginal soft capsule composition and preparation method thereof

The invention relates to a rapid-to-disintegrate hormone vaginal soft capsule shell. The hormone vaginal soft capsule shell consists of a compound capsule shell capable of rapidly disintegrating in asmall amount of weakly acidic vaginal fluid and a functional content; the capsule shell consists of 6...

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Hauptverfasser: YAO JIANXU, SUN JUNDI
Format: Patent
Sprache:chi ; eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator YAO JIANXU
SUN JUNDI
description The invention relates to a rapid-to-disintegrate hormone vaginal soft capsule shell. The hormone vaginal soft capsule shell consists of a compound capsule shell capable of rapidly disintegrating in asmall amount of weakly acidic vaginal fluid and a functional content; the capsule shell consists of 6%-12% of carrageenan, 10%-40% of modified starch, 10%-25% of plasticizer, 3%-5% of disintegrating agent, 0%-0.2% of preservative and water; and the functional content can be hormone drugs including progesterone, estriol, norethindrone, megestrol and the like. The invention further discloses a method for preparing the soft capsule shell by using the composition and a soft capsule prepared from the soft capsule shell. The vagina soft capsule shell provided by the invention has the advantages of rapid disintegration, excellent aging resistance, stable components and the like. 本发明涉及一种快速崩解的激素阴道软胶囊囊壳，由能够在少量的弱酸性阴道液中快速崩解的复配型囊壳和功能性内容物组成，所述囊壳由卡拉胶6%-12%、改性淀粉10%-40%、增塑剂10%-25%、崩解剂3%-5%、防腐剂0%-0.2%以及水组成，功能性内容物可以是黄体酮、雌三醇、炔诺酮、甲地孕酮
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The hormone vaginal soft capsule shell consists of a compound capsule shell capable of rapidly disintegrating in asmall amount of weakly acidic vaginal fluid and a functional content; the capsule shell consists of 6%-12% of carrageenan, 10%-40% of modified starch, 10%-25% of plasticizer, 3%-5% of disintegrating agent, 0%-0.2% of preservative and water; and the functional content can be hormone drugs including progesterone, estriol, norethindrone, megestrol and the like. The invention further discloses a method for preparing the soft capsule shell by using the composition and a soft capsule prepared from the soft capsule shell. The vagina soft capsule shell provided by the invention has the advantages of rapid disintegration, excellent aging resistance, stable components and the like. 本发明涉及一种快速崩解的激素阴道软胶囊囊壳，由能够在少量的弱酸性阴道液中快速崩解的复配型囊壳和功能性内容物组成，所述囊壳由卡拉胶6%-12%、改性淀粉10%-40%、增塑剂10%-25%、崩解剂3%-5%、防腐剂0%-0.2%以及水组成，功能性内容物可以是黄体酮、雌三醇、炔诺酮、甲地孕酮</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20210209&amp;DB=EPODOC&amp;CC=CN&amp;NR=112336698A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20210209&amp;DB=EPODOC&amp;CC=CN&amp;NR=112336698A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YAO JIANXU</creatorcontrib><creatorcontrib>SUN JUNDI</creatorcontrib><title>Rapid-to-disintegrate vaginal soft capsule composition and preparation method thereof</title><description>The invention relates to a rapid-to-disintegrate hormone vaginal soft capsule shell. 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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Rapid-to-disintegrate vaginal soft capsule composition and preparation method thereof
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