Preparation method and application range of 3-bromopyruvate lipid cubic liquid crystal

The invention discloses a preparation method and application range of a 3-bromopyruvate lipid cubic liquid crystal, and belongs to the technical field of biology. The preparation method comprises thefollowing steps: weighing 0.889 g of GMO and 0.111 g of F127, putting the GMO and the F127 into a beaker, and carrying out constant-temperature water bath at 60 DEG C; performing magnetic stirring until the mixture is completely molten, adding 26.67 mg of 3-BP, and slowly adding 25 ml of pure water preheated in advance into the oil phase to serve as a precursor solution; and carrying out high-pressure homogenization on the precursor solution under the conditions of 14900 psi and 9 cycles to obtain milk white 3-BP-LCNP. According to the preparation method, the influence of the dosage of an auxiliary material, a stabilizer, a dispersion phase and a medicine on a crystal form of the lipid cubic liquid crystal is preliminarily screened, a preparation prescription process is optimized by adopting orthogonal design, a p