Pharmaceutical composition of oseltamivir phosphate coated particles, as well as application and preparation method

The invention provides a pharmaceutical composition of oseltamivir phosphate coated particles, as well as application and a preparation method. The pharmaceutical composition comprises coated particles and drug-free particles, and the weight ratio of the coated particles to the drug-free particles i...

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Hauptverfasser: MA HAITAO, YU FANGLIN, XIAO XUYONG, GU JINMIAO, YU HONGXIA, LIU YUNTAO
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creator MA HAITAO
YU FANGLIN
XIAO XUYONG
GU JINMIAO
YU HONGXIA
LIU YUNTAO
description The invention provides a pharmaceutical composition of oseltamivir phosphate coated particles, as well as application and a preparation method. The pharmaceutical composition comprises coated particles and drug-free particles, and the weight ratio of the coated particles to the drug-free particles is (1: 10) to (1: 2); the coating particles comprise oseltamivir phosphate-containing medicinal particles and a coating layer, and the coating layer comprises xanthan gum and opacifier titanium dioxide; the oseltamivir phosphate-containing medicinal particles comprise oseltamivir phosphate, a pH regulator sodium citrate and citric acid, a flavoring agent essence and an adhesive pure water; and the weight ratio of oseltamivir phosphate to the pH regulator to the flavoring agent is 2: 3: 1. According to the oseltamivir phosphate coated particle pharmaceutical composition, the application and the preparation method provided by the invention, oseltamivir phosphate is prevented from being degradedby related auxiliary mat
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Pharmaceutical composition of oseltamivir phosphate coated particles, as well as application and preparation method
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