STABLE AQUEOUS ANTI-TAU ANTIBODY FORMULATIONS
The present disclosure provides stable, aqueous, buffered compositions comprising a high concentration of ABBV-8E12, such as a stable, aqueous buffered composition including ABBV-8E12 at a concentration of about 100 mg/ml, at least one buffer, an excipient, a surfactant, and optionally an antioxidan...
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| creator | SIEDLER MICHAEL APPENZELLER KERSTIN HULSMEYER MARTIN MEYER TANJA RINN CHRISTINE WILBERTZ AXEL SCHAKER-THEOBALD KATHRIN ANGSTENBERGER JONAS RIED CHRISTIAN KALETA KATHARINA |
| description | The present disclosure provides stable, aqueous, buffered compositions comprising a high concentration of ABBV-8E12, such as a stable, aqueous buffered composition including ABBV-8E12 at a concentration of about 100 mg/ml, at least one buffer, an excipient, a surfactant, and optionally an antioxidant.
本公开提供了包括高浓度的ABBV-8E12的稳定的水性缓冲组合物，如包含浓度为约100mg/ml的ABBV-8E12、至少一种缓冲液、赋形剂、表面活性剂以及任选地抗氧化剂的稳定的水性缓冲组合物。 |
| format | Patent |
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本公开提供了包括高浓度的ABBV-8E12的稳定的水性缓冲组合物，如包含浓度为约100mg/ml的ABBV-8E12、至少一种缓冲液、赋形剂、表面活性剂以及任选地抗氧化剂的稳定的水性缓冲组合物。</description><language>chi ; eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201127&DB=EPODOC&CC=CN&NR=112004827A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201127&DB=EPODOC&CC=CN&NR=112004827A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SIEDLER MICHAEL</creatorcontrib><creatorcontrib>APPENZELLER KERSTIN</creatorcontrib><creatorcontrib>HULSMEYER MARTIN</creatorcontrib><creatorcontrib>MEYER TANJA</creatorcontrib><creatorcontrib>RINN CHRISTINE</creatorcontrib><creatorcontrib>WILBERTZ AXEL</creatorcontrib><creatorcontrib>SCHAKER-THEOBALD KATHRIN</creatorcontrib><creatorcontrib>ANGSTENBERGER JONAS</creatorcontrib><creatorcontrib>RIED CHRISTIAN</creatorcontrib><creatorcontrib>KALETA KATHARINA</creatorcontrib><title>STABLE AQUEOUS ANTI-TAU ANTIBODY FORMULATIONS</title><description>The present disclosure provides stable, aqueous, buffered compositions comprising a high concentration of ABBV-8E12, such as a stable, aqueous buffered composition including ABBV-8E12 at a concentration of about 100 mg/ml, at least one buffer, an excipient, a surfactant, and optionally an antioxidant.
本公开提供了包括高浓度的ABBV-8E12的稳定的水性缓冲组合物，如包含浓度为约100mg/ml的ABBV-8E12、至少一种缓冲液、赋形剂、表面活性剂以及任选地抗氧化剂的稳定的水性缓冲组合物。</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNANDnF08nFVcAwMdfUPDVZw9Avx1A1xDAUznPxdIhXc_IN8Q30cQzz9_YJ5GFjTEnOKU3mhNDeDoptriLOHbmpBfnxqcUFicmpeakm8s5-hoZGBgYmFkbmjMTFqANKtJaQ</recordid><startdate>20201127</startdate><enddate>20201127</enddate><creator>SIEDLER MICHAEL</creator><creator>APPENZELLER KERSTIN</creator><creator>HULSMEYER MARTIN</creator><creator>MEYER TANJA</creator><creator>RINN CHRISTINE</creator><creator>WILBERTZ AXEL</creator><creator>SCHAKER-THEOBALD KATHRIN</creator><creator>ANGSTENBERGER JONAS</creator><creator>RIED CHRISTIAN</creator><creator>KALETA KATHARINA</creator><scope>EVB</scope></search><sort><creationdate>20201127</creationdate><title>STABLE AQUEOUS ANTI-TAU ANTIBODY FORMULATIONS</title><author>SIEDLER MICHAEL ; APPENZELLER KERSTIN ; HULSMEYER MARTIN ; MEYER TANJA ; RINN CHRISTINE ; WILBERTZ AXEL ; SCHAKER-THEOBALD KATHRIN ; ANGSTENBERGER JONAS ; RIED CHRISTIAN ; KALETA KATHARINA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN112004827A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>SIEDLER MICHAEL</creatorcontrib><creatorcontrib>APPENZELLER KERSTIN</creatorcontrib><creatorcontrib>HULSMEYER MARTIN</creatorcontrib><creatorcontrib>MEYER TANJA</creatorcontrib><creatorcontrib>RINN CHRISTINE</creatorcontrib><creatorcontrib>WILBERTZ AXEL</creatorcontrib><creatorcontrib>SCHAKER-THEOBALD KATHRIN</creatorcontrib><creatorcontrib>ANGSTENBERGER JONAS</creatorcontrib><creatorcontrib>RIED CHRISTIAN</creatorcontrib><creatorcontrib>KALETA KATHARINA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SIEDLER MICHAEL</au><au>APPENZELLER KERSTIN</au><au>HULSMEYER MARTIN</au><au>MEYER TANJA</au><au>RINN CHRISTINE</au><au>WILBERTZ AXEL</au><au>SCHAKER-THEOBALD KATHRIN</au><au>ANGSTENBERGER JONAS</au><au>RIED CHRISTIAN</au><au>KALETA KATHARINA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>STABLE AQUEOUS ANTI-TAU ANTIBODY FORMULATIONS</title><date>2020-11-27</date><risdate>2020</risdate><abstract>The present disclosure provides stable, aqueous, buffered compositions comprising a high concentration of ABBV-8E12, such as a stable, aqueous buffered composition including ABBV-8E12 at a concentration of about 100 mg/ml, at least one buffer, an excipient, a surfactant, and optionally an antioxidant.
本公开提供了包括高浓度的ABBV-8E12的稳定的水性缓冲组合物，如包含浓度为约100mg/ml的ABBV-8E12、至少一种缓冲液、赋形剂、表面活性剂以及任选地抗氧化剂的稳定的水性缓冲组合物。</abstract><oa>free_for_read</oa></addata></record> |
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| language | chi ; eng |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | STABLE AQUEOUS ANTI-TAU ANTIBODY FORMULATIONS |
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