Phloroglucinol and trimethylphloroglucinol injection and preparation method of injection
The invention provides a phloroglucinol and trimethylphloroglucinol injection and a preparation method thereof, and relates to the field of pharmaceutical preparations. The injection comprises phloroglucinol, trimethylphloroglucinol, sodium chloride and L-cysteine. The preparation method comprises t...
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| creator | CHEN SHI CHEN YING DENG XIAFEI CHEN LIANGLI TANG WEI ZHENG HU PAN YUE LI CHANGHAO GUO FEN |
| description | The invention provides a phloroglucinol and trimethylphloroglucinol injection and a preparation method thereof, and relates to the field of pharmaceutical preparations. The injection comprises phloroglucinol, trimethylphloroglucinol, sodium chloride and L-cysteine. The preparation method comprises the following steps: (1) heating water for injection, adding trimethylphloroglucinol, and uniformly stirring and dispersing; (2) after cooling, introducing carbon dioxide, adding phloroglucinol, sodium chloride and L-cysteine, and stirring until the solution is clear; and (3) sterilizing the solutionin a water bath after sterilizing and filtering the solution. The finally obtained injection is less in impurity quantity, the effect of the injection is consistent with that of an original product,and meanwhile, the problems that trimethylphloroglucinol is extremely difficult to dissolve and the content of trimethylphloroglucinol is unqualified due to adsorption in the preparation process are solved.
本发明提供了一种间苯三酚和三甲基间苯三 |
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本发明提供了一种间苯三酚和三甲基间苯三</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201030&DB=EPODOC&CC=CN&NR=111840259A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201030&DB=EPODOC&CC=CN&NR=111840259A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEN SHI</creatorcontrib><creatorcontrib>CHEN YING</creatorcontrib><creatorcontrib>DENG XIAFEI</creatorcontrib><creatorcontrib>CHEN LIANGLI</creatorcontrib><creatorcontrib>TANG WEI</creatorcontrib><creatorcontrib>ZHENG HU</creatorcontrib><creatorcontrib>PAN YUE</creatorcontrib><creatorcontrib>LI CHANGHAO</creatorcontrib><creatorcontrib>GUO FEN</creatorcontrib><title>Phloroglucinol and trimethylphloroglucinol injection and preparation method of injection</title><description>The invention provides a phloroglucinol and trimethylphloroglucinol injection and a preparation method thereof, and relates to the field of pharmaceutical preparations. The injection comprises phloroglucinol, trimethylphloroglucinol, sodium chloride and L-cysteine. The preparation method comprises the following steps: (1) heating water for injection, adding trimethylphloroglucinol, and uniformly stirring and dispersing; (2) after cooling, introducing carbon dioxide, adding phloroglucinol, sodium chloride and L-cysteine, and stirring until the solution is clear; and (3) sterilizing the solutionin a water bath after sterilizing and filtering the solution. The finally obtained injection is less in impurity quantity, the effect of the injection is consistent with that of an original product,and meanwhile, the problems that trimethylphloroglucinol is extremely difficult to dissolve and the content of trimethylphloroglucinol is unqualified due to adsorption in the preparation process are solved.
本发明提供了一种间苯三酚和三甲基间苯三</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZIgIyMjJL8pPzylNzszLz1FIzEtRKCnKzE0tyajMKUCVy8zLSk0uyczPA6sqKEotSCxKBPNByvNTFPLTEGp4GFjTEnOKU3mhNDeDoptriLOHbmpBfnxqcUFicmpeakm8s5-hoaGFiYGRqaWjMTFqAHhEO8g</recordid><startdate>20201030</startdate><enddate>20201030</enddate><creator>CHEN SHI</creator><creator>CHEN YING</creator><creator>DENG XIAFEI</creator><creator>CHEN LIANGLI</creator><creator>TANG WEI</creator><creator>ZHENG HU</creator><creator>PAN YUE</creator><creator>LI CHANGHAO</creator><creator>GUO FEN</creator><scope>EVB</scope></search><sort><creationdate>20201030</creationdate><title>Phloroglucinol and trimethylphloroglucinol injection and preparation method of injection</title><author>CHEN SHI ; CHEN YING ; DENG XIAFEI ; CHEN LIANGLI ; TANG WEI ; ZHENG HU ; PAN YUE ; LI CHANGHAO ; GUO FEN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN111840259A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2020</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CHEN SHI</creatorcontrib><creatorcontrib>CHEN YING</creatorcontrib><creatorcontrib>DENG XIAFEI</creatorcontrib><creatorcontrib>CHEN LIANGLI</creatorcontrib><creatorcontrib>TANG WEI</creatorcontrib><creatorcontrib>ZHENG HU</creatorcontrib><creatorcontrib>PAN YUE</creatorcontrib><creatorcontrib>LI CHANGHAO</creatorcontrib><creatorcontrib>GUO FEN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHEN SHI</au><au>CHEN YING</au><au>DENG XIAFEI</au><au>CHEN LIANGLI</au><au>TANG WEI</au><au>ZHENG HU</au><au>PAN YUE</au><au>LI CHANGHAO</au><au>GUO FEN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Phloroglucinol and trimethylphloroglucinol injection and preparation method of injection</title><date>2020-10-30</date><risdate>2020</risdate><abstract>The invention provides a phloroglucinol and trimethylphloroglucinol injection and a preparation method thereof, and relates to the field of pharmaceutical preparations. The injection comprises phloroglucinol, trimethylphloroglucinol, sodium chloride and L-cysteine. The preparation method comprises the following steps: (1) heating water for injection, adding trimethylphloroglucinol, and uniformly stirring and dispersing; (2) after cooling, introducing carbon dioxide, adding phloroglucinol, sodium chloride and L-cysteine, and stirring until the solution is clear; and (3) sterilizing the solutionin a water bath after sterilizing and filtering the solution. The finally obtained injection is less in impurity quantity, the effect of the injection is consistent with that of an original product,and meanwhile, the problems that trimethylphloroglucinol is extremely difficult to dissolve and the content of trimethylphloroglucinol is unqualified due to adsorption in the preparation process are solved.
本发明提供了一种间苯三酚和三甲基间苯三</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Phloroglucinol and trimethylphloroglucinol injection and preparation method of injection |
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