PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS BY ENZYMATIC REDUCTION AND NOVEL SYNTHESIS INTERMEDIATES
Subject-matter of the present invention is a process for preparing intermediates for the synthesis of optically active beta-amino alcohols by enzymatic reduction of the corresponding beta-amino ketones. Subject-matter of the invention are also said novel synthesis intermediates and the use thereof i...
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| creator | BERTOLINI GIORGIO BERTUOLO STEFANIA GARIS FARIS RONZONI SILVANO DI FABIO ROMANO MAIORANA STEFANO SADA MARA BIAGGI CINZIA NISIC FILIPPO PRANDI ADOLFO COLLI CORRADO BIANCHI ALDO |
| description | Subject-matter of the present invention is a process for preparing intermediates for the synthesis of optically active beta-amino alcohols by enzymatic reduction of the corresponding beta-amino ketones. Subject-matter of the invention are also said novel synthesis intermediates and the use thereof in the preparation of active pharmaceutical ingredients, among which vilanterol and the salts thereof.
本发明的主题是制备中间体的方法，该中间体用于通过酶还原相应的β-氨基酮来合成光学活性的β-氨基醇。本发明的主题还是所述新型合成中间体及其在制备活性药物成分中的用途，所述活性药物成分包括维兰特罗及其盐等。 |
| format | Patent |
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本发明的主题是制备中间体的方法，该中间体用于通过酶还原相应的β-氨基酮来合成光学活性的β-氨基醇。本发明的主题还是所述新型合成中间体及其在制备活性药物成分中的用途，所述活性药物成分包括维兰特罗及其盐等。</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjTEKwkAQRdNYiHqH8QApQkBiOdlMzMJmJuyugdiEIGslGohn8bwGtNDO6hX_8f4yejZWFDkHpVhoLDVoNR9AsydbU6HR03vzFYHreIbTDqQEabxWaEwHqLxuCXLyGGOtWQCNkkqMg7wD4lNX4-yCpeI4q8KAXABLS-Yr-XO5jhaX4TqFzYeraFuSV1UcxnsfpnE4h1t49IqTJMnSXbbfY_qP8wI1A0Lm</recordid><startdate>20201027</startdate><enddate>20201027</enddate><creator>BERTOLINI GIORGIO</creator><creator>BERTUOLO STEFANIA</creator><creator>GARIS FARIS</creator><creator>RONZONI SILVANO</creator><creator>DI FABIO ROMANO</creator><creator>MAIORANA STEFANO</creator><creator>SADA MARA</creator><creator>BIAGGI CINZIA</creator><creator>NISIC FILIPPO</creator><creator>PRANDI ADOLFO</creator><creator>COLLI CORRADO</creator><creator>BIANCHI ALDO</creator><scope>EVB</scope></search><sort><creationdate>20201027</creationdate><title>PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS BY ENZYMATIC REDUCTION AND NOVEL SYNTHESIS INTERMEDIATES</title><author>BERTOLINI GIORGIO ; BERTUOLO STEFANIA ; GARIS FARIS ; RONZONI SILVANO ; DI FABIO ROMANO ; MAIORANA STEFANO ; SADA MARA ; BIAGGI CINZIA ; NISIC FILIPPO ; PRANDI ADOLFO ; COLLI CORRADO ; BIANCHI ALDO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN111836899A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2020</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>BERTOLINI GIORGIO</creatorcontrib><creatorcontrib>BERTUOLO STEFANIA</creatorcontrib><creatorcontrib>GARIS FARIS</creatorcontrib><creatorcontrib>RONZONI SILVANO</creatorcontrib><creatorcontrib>DI FABIO ROMANO</creatorcontrib><creatorcontrib>MAIORANA STEFANO</creatorcontrib><creatorcontrib>SADA MARA</creatorcontrib><creatorcontrib>BIAGGI CINZIA</creatorcontrib><creatorcontrib>NISIC FILIPPO</creatorcontrib><creatorcontrib>PRANDI ADOLFO</creatorcontrib><creatorcontrib>COLLI CORRADO</creatorcontrib><creatorcontrib>BIANCHI ALDO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BERTOLINI GIORGIO</au><au>BERTUOLO STEFANIA</au><au>GARIS FARIS</au><au>RONZONI SILVANO</au><au>DI FABIO ROMANO</au><au>MAIORANA STEFANO</au><au>SADA MARA</au><au>BIAGGI CINZIA</au><au>NISIC FILIPPO</au><au>PRANDI ADOLFO</au><au>COLLI CORRADO</au><au>BIANCHI ALDO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS BY ENZYMATIC REDUCTION AND NOVEL SYNTHESIS INTERMEDIATES</title><date>2020-10-27</date><risdate>2020</risdate><abstract>Subject-matter of the present invention is a process for preparing intermediates for the synthesis of optically active beta-amino alcohols by enzymatic reduction of the corresponding beta-amino ketones. Subject-matter of the invention are also said novel synthesis intermediates and the use thereof in the preparation of active pharmaceutical ingredients, among which vilanterol and the salts thereof.
本发明的主题是制备中间体的方法，该中间体用于通过酶还原相应的β-氨基酮来合成光学活性的β-氨基醇。本发明的主题还是所述新型合成中间体及其在制备活性药物成分中的用途，所述活性药物成分包括维兰特罗及其盐等。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY SPIRITS VINEGAR WINE |
| title | PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS BY ENZYMATIC REDUCTION AND NOVEL SYNTHESIS INTERMEDIATES |
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