Epidermal growth factor receptor inhibitors

The present group of inventions relates to novel compounds having formula (I), and to the salts, solvates or stereoisomers thereof, as well as to a pharmaceutical composition, a method of inhibiting the biological activity of epidermal growth factor receptor (EGFR), a method of treating diseases or...

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Hauptverfasser:	MELESHINA MARINA VIKTOROVNA, SMETANIN ILIA ALEXEEVICH, KOZHEMYAKINA NATALIA VLADIMIROVNA, KASATKINA MARIIA ANDREEVNA, POPKOVA ALEKSANDRA VLADIMIROVNA, GORBUNOVA SVETLANA LEONIDOVNA, KULISH KIRILL IGOREVICH, MELCHAEVA OLGA ANATOLEVNA, MOROZOV DMITRY VALENTINOVICH, MAKSIMENKO ELENA ALEKSANDROVNA, SOLDATOVA IAROSLAVNA ALEXANDROVNA, MINDICH ALEKSEI LEONIDOVICH, ZAVIALOV KIRILL VADIMOVICH, BEKETOVA DARIA DMITRIEVNA, SHEKHAUTSOU ARTSIOM EVGENIEVICH, IAKOBSON GEORGII VIKTOROVICH, SILONOV SERGEY ALEKSANDROVICH
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present group of inventions relates to novel compounds having formula (I), and to the salts, solvates or stereoisomers thereof, as well as to a pharmaceutical composition, a method of inhibiting the biological activity of epidermal growth factor receptor (EGFR), a method of treating diseases or disorders mediated by EGFR activity, and the use of the claimed compounds or the aforementioned composition for treating a disease or a disorder mediated by EGFR activity. 本发明涉及新的式I化合物或其药学上可接受的盐、溶剂化物或立体异构体，还涉及药用组合物、用于抑制表皮生长因子受体(EGFR)的生物学活性的方法、用于治疗由EGFR激活介导的疾病或障碍的方法以及本发明化合物或本发明药用组合物用于治疗由EGFR的激活介导的疾病或障碍的用途。I。