Synthesis method of triarylmethane derivative

The invention discloses a method for synthesizing a triarylmethane derivative. The triarylmethane derivative is synthesized through a one-pot reaction of various substituted salicylaldehyde, aromaticboric acid and aromatic hydrocarbon by using iodine as a catalyst. The three different aryl groups ar...

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description The invention discloses a method for synthesizing a triarylmethane derivative. The triarylmethane derivative is synthesized through a one-pot reaction of various substituted salicylaldehyde, aromaticboric acid and aromatic hydrocarbon by using iodine as a catalyst. The three different aryl groups are introduced from salicylaldehyde, arylboronic acid and aromatic hydrocarbon which are low in priceand easy to obtain in one step under the condition of no alkali/ligand and completely without participation of metal catalysis, the reaction has very high chemical selectivity, and a triarylmethane derivative with completely asymmetric groups is provided. The method has the advantages of simple operation, short reaction time, cheap and easily available catalyst, low production cost, less pollution, simple post-treatment, and very high yield of the reaction. 本发明公开了一种合成三芳基甲烷衍生物的方法,它是以碘为催化剂,由各种取代水杨醛、芳香硼酸和芳烃"一锅"反应合成得到。这三种不同的芳基是在不含碱/配体的条件下,而且完全不用金属催化的参与,从价格低廉且容易获得的水杨醛、芳基硼酸和芳烃一步引入的,该反应具有很高的化学选择性,并提供了各种基团完全不对称的三芳基甲烷衍生物,该方法操作
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The triarylmethane derivative is synthesized through a one-pot reaction of various substituted salicylaldehyde, aromaticboric acid and aromatic hydrocarbon by using iodine as a catalyst. The three different aryl groups are introduced from salicylaldehyde, arylboronic acid and aromatic hydrocarbon which are low in priceand easy to obtain in one step under the condition of no alkali/ligand and completely without participation of metal catalysis, the reaction has very high chemical selectivity, and a triarylmethane derivative with completely asymmetric groups is provided. The method has the advantages of simple operation, short reaction time, cheap and easily available catalyst, low production cost, less pollution, simple post-treatment, and very high yield of the reaction. 本发明公开了一种合成三芳基甲烷衍生物的方法,它是以碘为催化剂,由各种取代水杨醛、芳香硼酸和芳烃"一锅"反应合成得到。这三种不同的芳基是在不含碱/配体的条件下,而且完全不用金属催化的参与,从价格低廉且容易获得的水杨醛、芳基硼酸和芳烃一步引入的,该反应具有很高的化学选择性,并提供了各种基团完全不对称的三芳基甲烷衍生物,该方法操作</description><language>chi ; eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; APPARATUS THEREFOR ; CHEMISTRY ; GENERAL METHODS OF ORGANIC CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200804&amp;DB=EPODOC&amp;CC=CN&amp;NR=111484419A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200804&amp;DB=EPODOC&amp;CC=CN&amp;NR=111484419A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>XU DAZHEN</creatorcontrib><creatorcontrib>YU YAQIN</creatorcontrib><title>Synthesis method of triarylmethane derivative</title><description>The invention discloses a method for synthesizing a triarylmethane derivative. 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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Synthesis method of triarylmethane derivative
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