Continuous synthesis method for 2-methyl-5-nitroimidazole

The invention provides a continuous synthesis method for 2-methyl-5-nitroimidazole. The 2-methyl-5-nitroimidazole is synthesized in a micro-channel reactor. The synthesis method provided by the invention can realize continuous synthesis, is safe and stable in production process, extremely short in r...

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Hauptverfasser: WANG WEI, XIAO SHUHUAN, REN MIAOMIAO, SHENG ZHEN, CAI WENJING, ZHANG BENSONG
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creator WANG WEI
XIAO SHUHUAN
REN MIAOMIAO
SHENG ZHEN
CAI WENJING
ZHANG BENSONG
description The invention provides a continuous synthesis method for 2-methyl-5-nitroimidazole. The 2-methyl-5-nitroimidazole is synthesized in a micro-channel reactor. The synthesis method provided by the invention can realize continuous synthesis, is safe and stable in production process, extremely short in reaction time and high in yield, and can reduce the usage amount of concentrated sulfuric acid and lower cost. 本发明提供了一种2-甲基-5-硝基咪唑的连续合成方法,所述合成在微通道反应器中进行。本发明提供的合成方法可实现连续化合成,并且生产过程安全、平稳;同时反应时间极短且收率较高;还可以降低浓硫酸的用量,减少成本。
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HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Continuous synthesis method for 2-methyl-5-nitroimidazole
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