Method of purifying glycosylated protein from host cell galectins and other contaminants

A method for purifying a glycosylated recombinant protein of interest from a contaminant is disclosed that is suitable for industrial production purposes to remove gelactins and other host cell contaminants, such as metallic cations, from recombinant therapeutic proteins. 公开了一种从污染物中纯化经糖基化的重组目的蛋白的方法，...

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Hauptverfasser:	MCCLURE MEGAN J, CONNELL-CROWLEY LISA A, GILLESPIE RONALD O
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A method for purifying a glycosylated recombinant protein of interest from a contaminant is disclosed that is suitable for industrial production purposes to remove gelactins and other host cell contaminants, such as metallic cations, from recombinant therapeutic proteins. 公开了一种从污染物中纯化经糖基化的重组目的蛋白的方法，该方法适用于工业生产目的，以从重组的治疗性蛋白质中去除半乳糖凝集素和其他宿主细胞污染物(例如金属阳离子)。