Personalized immunotherapy against several neuronal and brain tumors

The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in com...

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Hauptverfasser: SONG COLETTE, HILF NORBERT, WALTER STEFFEN, SCHORR OLIVER, WEINSCHENK TONI, SINGH HARPREET, FRITSCHE JENS, KUTTRUFF-COQUI SABRINA
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creator SONG COLETTE
HILF NORBERT
WALTER STEFFEN
SCHORR OLIVER
WEINSCHENK TONI
SINGH HARPREET
FRITSCHE JENS
KUTTRUFF-COQUI SABRINA
description The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cellsthat can be used in vaccine compositions for eliciting anti-tumor immune responses. 本发明涉及用于免疫治疗方法的肽、核酸和细胞。特别是,本发明涉及癌症的免疫疗法。本发明还涉及单独使用或与其他肿瘤相关肽(刺激抗肿瘤免疫反应疫苗复合物的活性药物成分)联合使用的肿瘤相关细胞毒性T辅助细胞(CTL)肽表位。本发明涉及肽序列及其变体,它们源自可用于引发抗肿瘤免疫反应的疫苗组合物中的人肿瘤HLA-I类和II类分子。
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Personalized immunotherapy against several neuronal and brain tumors
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