INTERMEDIATES USEFUL FOR THE SYNTHESIS OF A SELECTIVE INHIBITOR AGAINST PROTEIN KINASE AND PROCESSES FOR PREPARING THE SAME
The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and...
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| creator | LEE DOO-BYUNG KHOO JA-HEOUK OH SANG-HO LEE JUN-SUP SHIN WOO-SEOB LEE JUNG-AE JU HYUN LIM JONGUL JEON SANG-SEOL |
| description | The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.
本发明提供了可用于合成对蛋白激酶，尤其是对突变表皮生长因子受体的蛋白激酶具有选择性抑制活性的氨基嘧啶衍生物或其药学上可接受的盐的中间体；及其制备方法。而且，本发明提供了可用于制备其的一种或多种所述方法的新型中间体。 |
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本发明提供了可用于合成对蛋白激酶，尤其是对突变表皮生长因子受体的蛋白激酶具有选择性抑制活性的氨基嘧啶衍生物或其药学上可接受的盐的中间体；及其制备方法。而且，本发明提供了可用于制备其的一种或多种所述方法的新型中间体。</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200616&DB=EPODOC&CC=CN&NR=111295381A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200616&DB=EPODOC&CC=CN&NR=111295381A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEE DOO-BYUNG</creatorcontrib><creatorcontrib>KHOO JA-HEOUK</creatorcontrib><creatorcontrib>OH SANG-HO</creatorcontrib><creatorcontrib>LEE JUN-SUP</creatorcontrib><creatorcontrib>SHIN WOO-SEOB</creatorcontrib><creatorcontrib>LEE JUNG-AE</creatorcontrib><creatorcontrib>JU HYUN</creatorcontrib><creatorcontrib>LIM JONGUL</creatorcontrib><creatorcontrib>JEON SANG-SEOL</creatorcontrib><title>INTERMEDIATES USEFUL FOR THE SYNTHESIS OF A SELECTIVE INHIBITOR AGAINST PROTEIN KINASE AND PROCESSES FOR PREPARING THE SAME</title><description>The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.
本发明提供了可用于合成对蛋白激酶，尤其是对突变表皮生长因子受体的蛋白激酶具有选择性抑制活性的氨基嘧啶衍生物或其药学上可接受的盐的中间体；及其制备方法。而且，本发明提供了可用于制备其的一种或多种所述方法的新型中间体。</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjMEKgkAQQL10iOofpg_osElQx0lndUhH2VmDTiKxnaIEu_XzKfUBnR48Hm8evVk8uZJSRk8KjZJtCrCVA58T6EVGKCtUFhCUCko8nwlYcj6yHzPMkEU91K7yxAInFlQClHRSCamO2-lXO6rRsWTfM5a0jGa37j6E1Y-LaG3JJ_km9M82DH13DY_wahMxxmwPu3hvMP6n-QBcnTrZ</recordid><startdate>20200616</startdate><enddate>20200616</enddate><creator>LEE DOO-BYUNG</creator><creator>KHOO JA-HEOUK</creator><creator>OH SANG-HO</creator><creator>LEE JUN-SUP</creator><creator>SHIN WOO-SEOB</creator><creator>LEE JUNG-AE</creator><creator>JU HYUN</creator><creator>LIM JONGUL</creator><creator>JEON SANG-SEOL</creator><scope>EVB</scope></search><sort><creationdate>20200616</creationdate><title>INTERMEDIATES USEFUL FOR THE SYNTHESIS OF A SELECTIVE INHIBITOR AGAINST PROTEIN KINASE AND PROCESSES FOR PREPARING THE SAME</title><author>LEE DOO-BYUNG ; KHOO JA-HEOUK ; OH SANG-HO ; LEE JUN-SUP ; SHIN WOO-SEOB ; LEE JUNG-AE ; JU HYUN ; LIM JONGUL ; JEON SANG-SEOL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN111295381A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>LEE DOO-BYUNG</creatorcontrib><creatorcontrib>KHOO JA-HEOUK</creatorcontrib><creatorcontrib>OH SANG-HO</creatorcontrib><creatorcontrib>LEE JUN-SUP</creatorcontrib><creatorcontrib>SHIN WOO-SEOB</creatorcontrib><creatorcontrib>LEE JUNG-AE</creatorcontrib><creatorcontrib>JU HYUN</creatorcontrib><creatorcontrib>LIM JONGUL</creatorcontrib><creatorcontrib>JEON SANG-SEOL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LEE DOO-BYUNG</au><au>KHOO JA-HEOUK</au><au>OH SANG-HO</au><au>LEE JUN-SUP</au><au>SHIN WOO-SEOB</au><au>LEE JUNG-AE</au><au>JU HYUN</au><au>LIM JONGUL</au><au>JEON SANG-SEOL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>INTERMEDIATES USEFUL FOR THE SYNTHESIS OF A SELECTIVE INHIBITOR AGAINST PROTEIN KINASE AND PROCESSES FOR PREPARING THE SAME</title><date>2020-06-16</date><risdate>2020</risdate><abstract>The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.
本发明提供了可用于合成对蛋白激酶，尤其是对突变表皮生长因子受体的蛋白激酶具有选择性抑制活性的氨基嘧啶衍生物或其药学上可接受的盐的中间体；及其制备方法。而且，本发明提供了可用于制备其的一种或多种所述方法的新型中间体。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | INTERMEDIATES USEFUL FOR THE SYNTHESIS OF A SELECTIVE INHIBITOR AGAINST PROTEIN KINASE AND PROCESSES FOR PREPARING THE SAME |
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