Application of Stemmacantha carthamoides alcohol extract in preparation of drugs for preventing and/or treating myocardial ischemic diseases

The invention discloses application of a Stemmacantha carthamoides alcohol extract in preparation of drugs for preventing and/or treating myocardial ischemic diseases and belongs to the fields of medicine and health. The Stemmacantha carthamoides alcohol extract can be used for alleviating an oxidat...

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Hauptverfasser: LYU XIAOHAN, ZHENG ZIHAN, WANG WEIRONG, YANG GUANGDE, WANG JIANJIANG, WANG BO, LIN RONG, CHEN LIFANG, XIAN YUSHAN, YAO FENG, GAO HONGQIAN, WANG GUAN, JIN ZHEN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses application of a Stemmacantha carthamoides alcohol extract in preparation of drugs for preventing and/or treating myocardial ischemic diseases and belongs to the fields of medicine and health. The Stemmacantha carthamoides alcohol extract can be used for alleviating an oxidative stress reaction and improving an energy metabolism level through activating Nrf2, thereby improving myocardial ischemic anoxic diseases; and the Stemmacantha carthamoides alcohol extract is obtained through carrying out reflux extraction by employing an ethanol aqueous solution, so that the prepared Stemmacantha carthamoides alcohol extract is a natural product and is high in treatment effect and minimal in side effect. 本发明公开了鹿草醇提物在制备预防和/或治疗心肌缺血性疾病药物中的应用,属于医药卫生领域。鹿草醇提物可通过激活Nrf2来减轻氧化应激反应和改善能量代谢水平,从而改善心肌缺血缺氧性疾病;采用乙醇水溶液回流提取得到鹿草醇提液,制备得到的鹿草醇提物为天然产物,疗效高,副作用小。