Anthraquinone compound extracted and separated from cassia seeds, and method and application of anthraquinone compound
The invention discloses an anthraquinone compound extracted and separated from cassia seeds, and a method and application of the anthraquinone compound. The anthraquinone compound has a structure represented by a formula (I). The compound is obtained by taking dried and crushed cassia seeds as a raw...
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| creator | ZHANG JUQIONG XIAO BIN CHEN CHONG LIU JUN BAI LANHUI ZHONG YU LI YUANZHI LIU DING LI BO |
| description | The invention discloses an anthraquinone compound extracted and separated from cassia seeds, and a method and application of the anthraquinone compound. The anthraquinone compound has a structure represented by a formula (I). The compound is obtained by taking dried and crushed cassia seeds as a raw material through the technical steps of ethanol reflux extraction, ethyl acetate extraction, AB-8 column chromatography separation and purification, high-pressure preparation and separation by C18 reverse-phase chromatography filler, and the like. The compound is a novel medicinal compound with pharmacological activity, has a good inhibition effect on staphylococcus aureus, can be used for preparing antibacterial drugs, and provides reliable basis for preparation of novel antibacterial drugs, pharmaceutical research of anthraquinone substances and the like.
本发明公开了一种从决明子中提取分离的蒽醌类化合物及其方法和应用，其结构式如（Ⅰ）所示。该化合物是以干燥粉碎后的决明子为原料，经乙醇回流提取、乙酸乙酯萃取、AB-8柱层析分离纯化、C18反相色谱填料高压制备分离等工艺步骤提取分离得到，为一种具有药理活性的新的药用化合物，对金黄色葡萄球菌具有很好的抑制效果，可作为在制备抗 |
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本发明公开了一种从决明子中提取分离的蒽醌类化合物及其方法和应用，其结构式如（Ⅰ）所示。该化合物是以干燥粉碎后的决明子为原料，经乙醇回流提取、乙酸乙酯萃取、AB-8柱层析分离纯化、C18反相色谱填料高压制备分离等工艺步骤提取分离得到，为一种具有药理活性的新的药用化合物，对金黄色葡萄球菌具有很好的抑制效果，可作为在制备抗</description><language>chi ; eng</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SUGARS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200428&DB=EPODOC&CC=CN&NR=111072735A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200428&DB=EPODOC&CC=CN&NR=111072735A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZHANG JUQIONG</creatorcontrib><creatorcontrib>XIAO BIN</creatorcontrib><creatorcontrib>CHEN CHONG</creatorcontrib><creatorcontrib>LIU JUN</creatorcontrib><creatorcontrib>BAI LANHUI</creatorcontrib><creatorcontrib>ZHONG YU</creatorcontrib><creatorcontrib>LI YUANZHI</creatorcontrib><creatorcontrib>LIU DING</creatorcontrib><creatorcontrib>LI BO</creatorcontrib><title>Anthraquinone compound extracted and separated from cassia seeds, and method and application of anthraquinone compound</title><description>The invention discloses an anthraquinone compound extracted and separated from cassia seeds, and a method and application of the anthraquinone compound. The anthraquinone compound has a structure represented by a formula (I). The compound is obtained by taking dried and crushed cassia seeds as a raw material through the technical steps of ethanol reflux extraction, ethyl acetate extraction, AB-8 column chromatography separation and purification, high-pressure preparation and separation by C18 reverse-phase chromatography filler, and the like. The compound is a novel medicinal compound with pharmacological activity, has a good inhibition effect on staphylococcus aureus, can be used for preparing antibacterial drugs, and provides reliable basis for preparation of novel antibacterial drugs, pharmaceutical research of anthraquinone substances and the like.
本发明公开了一种从决明子中提取分离的蒽醌类化合物及其方法和应用，其结构式如（Ⅰ）所示。该化合物是以干燥粉碎后的决明子为原料，经乙醇回流提取、乙酸乙酯萃取、AB-8柱层析分离纯化、C18反相色谱填料高压制备分离等工艺步骤提取分离得到，为一种具有药理活性的新的药用化合物，对金黄色葡萄球菌具有很好的抑制效果，可作为在制备抗</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjL0KwjAURrs4iPoOcVcwFulciuLk5F4uyQ0NNPfG3FR8fOPP6OD0cQ6Hb17dW8pDgtvkiQmV4RB5IqvwkROYjFZBIcEICV7kEgdlQMRDsWhl8w4C5oE_LcQ4egPZMyl2Rf36X1YzB6Pg6ruLan06XrvzFiP3KBEMEua-u2itd82-qQ9t_U_zBHw2Rh8</recordid><startdate>20200428</startdate><enddate>20200428</enddate><creator>ZHANG JUQIONG</creator><creator>XIAO BIN</creator><creator>CHEN CHONG</creator><creator>LIU JUN</creator><creator>BAI LANHUI</creator><creator>ZHONG YU</creator><creator>LI YUANZHI</creator><creator>LIU DING</creator><creator>LI BO</creator><scope>EVB</scope></search><sort><creationdate>20200428</creationdate><title>Anthraquinone compound extracted and separated from cassia seeds, and method and application of anthraquinone compound</title><author>ZHANG JUQIONG ; XIAO BIN ; CHEN CHONG ; LIU JUN ; BAI LANHUI ; ZHONG YU ; LI YUANZHI ; LIU DING ; LI BO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN111072735A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>ZHANG JUQIONG</creatorcontrib><creatorcontrib>XIAO BIN</creatorcontrib><creatorcontrib>CHEN CHONG</creatorcontrib><creatorcontrib>LIU JUN</creatorcontrib><creatorcontrib>BAI LANHUI</creatorcontrib><creatorcontrib>ZHONG YU</creatorcontrib><creatorcontrib>LI YUANZHI</creatorcontrib><creatorcontrib>LIU DING</creatorcontrib><creatorcontrib>LI BO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZHANG JUQIONG</au><au>XIAO BIN</au><au>CHEN CHONG</au><au>LIU JUN</au><au>BAI LANHUI</au><au>ZHONG YU</au><au>LI YUANZHI</au><au>LIU DING</au><au>LI BO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Anthraquinone compound extracted and separated from cassia seeds, and method and application of anthraquinone compound</title><date>2020-04-28</date><risdate>2020</risdate><abstract>The invention discloses an anthraquinone compound extracted and separated from cassia seeds, and a method and application of the anthraquinone compound. The anthraquinone compound has a structure represented by a formula (I). The compound is obtained by taking dried and crushed cassia seeds as a raw material through the technical steps of ethanol reflux extraction, ethyl acetate extraction, AB-8 column chromatography separation and purification, high-pressure preparation and separation by C18 reverse-phase chromatography filler, and the like. The compound is a novel medicinal compound with pharmacological activity, has a good inhibition effect on staphylococcus aureus, can be used for preparing antibacterial drugs, and provides reliable basis for preparation of novel antibacterial drugs, pharmaceutical research of anthraquinone substances and the like.
本发明公开了一种从决明子中提取分离的蒽醌类化合物及其方法和应用，其结构式如（Ⅰ）所示。该化合物是以干燥粉碎后的决明子为原料，经乙醇回流提取、乙酸乙酯萃取、AB-8柱层析分离纯化、C18反相色谱填料高压制备分离等工艺步骤提取分离得到，为一种具有药理活性的新的药用化合物，对金黄色葡萄球菌具有很好的抑制效果，可作为在制备抗</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
| title | Anthraquinone compound extracted and separated from cassia seeds, and method and application of anthraquinone compound |
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