METHODS FOR CRYOGENIC STORAGE

The present disclosure relates to methods comprising cryogenically storing cells from a biological sample derived from a donor, in particular an apheresis sample, wherein the cells are frozen in a controlled rate freezer using a stepwise freezing profile comprising at least one step, wherein the sam...

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Hauptverfasser: GUNTHER JON CHARLES, POLLOCK KATHRYN, CHURCH SARA ELIZABETH
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Sprache:chi ; eng
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creator GUNTHER JON CHARLES
POLLOCK KATHRYN
CHURCH SARA ELIZABETH
description The present disclosure relates to methods comprising cryogenically storing cells from a biological sample derived from a donor, in particular an apheresis sample, wherein the cells are frozen in a controlled rate freezer using a stepwise freezing profile comprising at least one step, wherein the sample and/or chamber is cooled at a rate greater than 1 deg C per minute, and wherein the cells may comprise or be enriched for T cells. Further aspects relate e.g. to the point in time at which the cells are obtained from the donor, the storage time, shipping the cells to a storage facility before orafter cryogenic freezing, the sample container being marked with codes or identifiers for cataloging the cells, administering a therapeutically effective amount of a composition comprising engineeredT cells generated from the cryogenically frozen cells to a subject in need thereof; and treatment of the donor for a disease, in particular cancer. 本公开内容涉及包括低温储存来自生物样品、特别是单采术样品的细胞的方法,所述生物样品源自供体,其中使用包括至少一个步骤的逐步冷冻谱将细胞冷冻在受控速率冷冻器
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Further aspects relate e.g. to the point in time at which the cells are obtained from the donor, the storage time, shipping the cells to a storage facility before orafter cryogenic freezing, the sample container being marked with codes or identifiers for cataloging the cells, administering a therapeutically effective amount of a composition comprising engineeredT cells generated from the cryogenically frozen cells to a subject in need thereof; and treatment of the donor for a disease, in particular cancer. 本公开内容涉及包括低温储存来自生物样品、特别是单采术样品的细胞的方法,所述生物样品源自供体,其中使用包括至少一个步骤的逐步冷冻谱将细胞冷冻在受控速率冷冻器</description><language>chi ; eng</language><subject>AGRICULTURE ; ANIMAL HUSBANDRY ; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES ; FISHING ; FORESTRY ; HUMAN NECESSITIES ; HUNTING ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PEST REPELLANTS OR ATTRACTANTS ; PLANT GROWTH REGULATORS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF ; TRAPPING</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200324&amp;DB=EPODOC&amp;CC=CN&amp;NR=110913690A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200324&amp;DB=EPODOC&amp;CC=CN&amp;NR=110913690A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GUNTHER JON CHARLES</creatorcontrib><creatorcontrib>POLLOCK KATHRYN</creatorcontrib><creatorcontrib>CHURCH SARA ELIZABETH</creatorcontrib><title>METHODS FOR CRYOGENIC STORAGE</title><description>The present disclosure relates to methods comprising cryogenically storing cells from a biological sample derived from a donor, in particular an apheresis sample, wherein the cells are frozen in a controlled rate freezer using a stepwise freezing profile comprising at least one step, wherein the sample and/or chamber is cooled at a rate greater than 1 deg C per minute, and wherein the cells may comprise or be enriched for T cells. 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subjects AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TRAPPING
title METHODS FOR CRYOGENIC STORAGE
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