Bioreactor cell culture quality evaluation method

The invention discloses a bioreactor cell culture quality evaluation method, and relates to the technical field of bioreactors. The bioreactor cell culture quality evaluation method comprises image enhancement, image segmentation, smoothing processing, connected region extraction, standard cell area judgment and cell distribution statistics, and completes automatic evaluation of the cell culture quality through statistics of the number of cells. According to the bioreactor cell culture quality evaluation method, the growth state of the cultured cells can be automatically evaluated, and a reliable guarantee means is provided for promoting the application of a large-scale cell culture technology in a cell factory. 本发明公开了生物反应器细胞培养质量评价方法，涉及生物反应器技术领域，方法包括图像增强、图像分割、平滑处理、连通区域提取、标准细胞面积判定和细胞分布统计，通过对细胞个数的统计即可完成对细胞培养质量的自动评价。本发明的方法可以实现对所培养细胞的生长状态自动评价，为推动细胞工厂大规模细胞培养技术应用提供了一种可靠的保障手段。