SURGICAL STAPLER WITH CONTROLLED HEALING

Methods and devices are provided for promoting wound healing. In general, surgical staplers and staple components are provided having an effective amount of at least matrix metalloproteinase (MMP) inhibitor being effective to prevent MMP-mediated extracellular matrix degeneration during wound healin...

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Bibliographische Detailangaben
Hauptverfasser: WIDENHOUSE TAMARA S, SHELTON IV FREDERICK E
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Methods and devices are provided for promoting wound healing. In general, surgical staplers and staple components are provided having an effective amount of at least matrix metalloproteinase (MMP) inhibitor being effective to prevent MMP-mediated extracellular matrix degeneration during wound healing in tissue. 本发明提供了用于促进伤口愈合的方法和装置。一般来讲,提供了具有有效量的至少基质金属蛋白酶(MMP)抑制剂的外科缝合器和钉部件,该抑制剂在伤口在组织中愈合期间有效防止MMP介导的细胞外基质变性。