Novel cephalosporin antibiotics and processes for preparation thereof

The present invention relates to a cephalosporin compound represented by the following general formula (I) : its pharmaceutically acceptable non-toxic salt, physiologically hydrolyzable ester, hydrate or solvate, or isomers thereof, in which R represents hydrogen or an amino-protecting group, R and...

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Hauptverfasser: JAE HONG YEO, CHAN SIK BANG, JONG CHAN LIM
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creator JAE HONG YEO
CHAN SIK BANG
JONG CHAN LIM
description The present invention relates to a cephalosporin compound represented by the following general formula (I) : its pharmaceutically acceptable non-toxic salt, physiologically hydrolyzable ester, hydrate or solvate, or isomers thereof, in which R represents hydrogen or an amino-protecting group, R and R can be identical or different and independently of one another represent hydrogen or a hydroxy-protecting group, or R and R together can form a cyclic diol-protecting group, R represents hydrogen or a carboxyl-protecting group, R , R and R independently of one another represent hydrogen, amino or substituted amino, hydroxy, alkoxy, C1-4 alkyl, carboxyl or alkoxycarbonyl, or R and R together with the carbon atoms to which they are attached can form a C3-7 cycle, and Q represents CH or N, and to a process for preparation thereof and a pharmaceutical composition containing the compound (I) as an active ingredient.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Novel cephalosporin antibiotics and processes for preparation thereof
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