Novel macrolides and the use thereof

Compounds of the formula in which R1 is hydroxyl, 2-hydroxyethoxy, C1-C4-alkoxy, C1-C4-alkanoyloxy, halogen, amine, azide, a keto, p-nitrobenzenesulphonyl or a pyranyloxy group of the formula in which X is a group of the formula or in which R3 is hydroxyl, C1-C4-alkanoyloxy or organic sulphonyloxy,...

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Hauptverfasser: KAI UWE BINDSEIL, AXEL ZEECK, CLAUDIA BODDIEN
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creator KAI UWE BINDSEIL
AXEL ZEECK
CLAUDIA BODDIEN
description Compounds of the formula in which R1 is hydroxyl, 2-hydroxyethoxy, C1-C4-alkoxy, C1-C4-alkanoyloxy, halogen, amine, azide, a keto, p-nitrobenzenesulphonyl or a pyranyloxy group of the formula in which X is a group of the formula or in which R3 is hydroxyl, C1-C4-alkanoyloxy or organic sulphonyloxy, and R4 is hydroxyl or carbamoyloxy, R2 is hydrogen, hydroperoxy, hydroxyl or methoxy, Y is a group of formula or in which R5 is hydroxyl or C1-C4-alkanoyloxy, and R6 and R7 are independently of one another, hydrogen or methyl, are suitable for the production of a drug for the prophylaxis and treatment of diseases which respond to inhibition of the osteoclast proton pump.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
DERIVATIVES THEREOF
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
SUGARS
VINEGAR
WINE
title Novel macrolides and the use thereof
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