Production method of 1-acetyl-2-pyrrolidone
The invention discloses a production method of 1-acetyl-2-pyrrolidone. The method includes the steps of: taking 1, 3-propylene glycol, ammonia water, methyl acetate and methyl formate as the raw materials, carrying out amination, addition and cyclization reactions in a tubular fixed bed reactor unde...
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| creator | SONG GUOQUAN YANG LI WU ZHENGLING LIANG BIN YAN GUANGXUE ZHOU SHUFEI WU YANBIN LI QINGXIA XIAO QIANG |
| description | The invention discloses a production method of 1-acetyl-2-pyrrolidone. The method includes the steps of: taking 1, 3-propylene glycol, ammonia water, methyl acetate and methyl formate as the raw materials, carrying out amination, addition and cyclization reactions in a tubular fixed bed reactor under the action of a copper-based catalyst to obtain a 1-acetyl-2-pyrrolidone crude product, and further performing purification to obtain the 1-acetyl-2-pyrrolidone. The method provided by the invention has the characteristics of high catalyst catalytic activity, mild reaction conditions and simple technological operation, and the obtained product has yield of greater than or equal to 98.4%, selectivity of greater than or equal to 99.0%, purity of higher than or equal to 99.9%, a water content ofsmaller than or equal to 40ppm, and an ammonia content of less than or equal to 2ppm, thus meeting the requirements of downstream medicine, fine chemical intermediates and other fields.
本发明公开了一种1-乙酰基-2-吡咯烷酮的生产方法，包括以下步骤：以1,3-丙 |
| format | Patent |
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本发明公开了一种1-乙酰基-2-吡咯烷酮的生产方法，包括以下步骤：以1,3-丙</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL THEIR RELEVANT APPARATUS TRANSPORTING |
| title | Production method of 1-acetyl-2-pyrrolidone |
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