Clean preparation method of amorolfine hydrochloride intermediate

The invention discloses a clean preparation method of an amorolfine hydrochloride intermediate, and more specially relates to a preparation method of 4-iodo-tert-pentyl-benzene. According to the cleanpreparation method, a target product is prepared from tert-Pentylbenzene through iodination. The raw materials and auxiliary materials are nontoxic or low in toxicity, cheap, and easily available; operation is simple; cost is low; the clean preparation method is suitable for industrialized production; and the quality is capable of reaching an ideal level. 一种盐酸阿莫罗芬中间体的清洁制备方法本发明涉及一种盐酸阿莫罗芬中间体的清洁制备方法，即4-碘代叔戊基苯的制备方法，它由叔戊基苯经碘代反应制得目标产物。本发明提供了一种合成盐酸阿莫罗芬中间体的新制备方法，具有原辅料无毒、低毒，价廉易得，操作简单，成本低，适合工业化生产，其质量可达到满意水平。