1,3-oxazino-1,2,3-triazole derivatives and synthesis method and application thereof

The invention discloses 1,3-oxazino 1,2,3-triazole derivatives and a synthesis method and application thereof, belonging to the technical field of pesticides and organic synthesis. The structural formula of the 1,3-oxazino 1,2,3-triazole derivative is or wherein R1 is H, Me or Cl, R2 is Cl, Br, F or Me, and R3 is pyridyl or thienyl; according to the invention, 1-o-hydroxymethylaryl-4-aryl-1,2,3-triazole is taken as a raw material to undergo selective carbon-oxygen coupling reaction under the catalysis of a "transition metal/oxidant" system to selectively generate 1,3-oxazino-1,2,3-triazole derivatives. The 1,3-oxazino 1,2,3-triazole derivatives contain oxazine and 1,2,3-triazole ring structural units at the same time, and have good inhibition effect on pathogenic bacteria of root rot of notoginseng. 本发明公开了1,3-噁嗪并1,2,3-三氮唑类衍生物及其合成方法与应用，属于农药及有机合成技术领域。本发明1,3-噁嗪并1,2,3-三氮唑类衍生物的结构式为或其中，R为H、Me或Cl，R为Cl、Br、F或Me，R为吡啶基或噻吩基；本发明以1-邻羟甲芳基-4-芳基-1,2,3-三氮唑为原料，在"过渡金属/氧化剂"体系催化下发生选择性碳-氧偶联反应，选择性生成1,3-噁嗪并1,2,3-三氮唑衍生物。本发明1,3-噁嗪并1,2,