Method for continuously preparing tulathromycin by adopting microchannel reactor
The invention relates to a method for continuously preparing tulathromycin by adopting a microchannel reactor. By adopting the microchannel reactor which has a large specific surface area to continuously prepare tulathromycin, the advantages are brought that the heat exchange efficiency and the mixi...
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| creator | TIAN ZHENPING XIA HOUQI LIU QUANCAI KONG MEI NING SHUQUN FANG MINGFENG MA QINGZHU |
| description | The invention relates to a method for continuously preparing tulathromycin by adopting a microchannel reactor. By adopting the microchannel reactor which has a large specific surface area to continuously prepare tulathromycin, the advantages are brought that the heat exchange efficiency and the mixing efficiency are extremely high, and precise temperature control and instantaneous mixing of reaction materials in a precise ratio can be achieved, so that the mass transfer efficiency of the microchannel reactor is very high; continuous reaction is achieved by adopting the microchannel reactor sothat working hours can be greatly shortened by 5-8 hours compared with that of the conventional method, the conversion rate is increased while reaction is shortened, by-products (ring-opening impurities) are reduced, and the purity of the product is improved.
本发明涉及一种利用微通道反应器连续式制备泰拉霉素的方法，该方法利用微通道反应器连续式制备泰拉霉素，微通道反应器有极大的比表面积，由此带来的优势是极大的换热效率和混合效率，能实现对温度的精确控制和对反应物料以精确配比瞬间混合，因此微反应器的传质效率非常高，且为连续式反应，能够大大缩短工时，相比传统缩短了5-8个小时，缩短反应的同时 |
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本发明涉及一种利用微通道反应器连续式制备泰拉霉素的方法，该方法利用微通道反应器连续式制备泰拉霉素，微通道反应器有极大的比表面积，由此带来的优势是极大的换热效率和混合效率，能实现对温度的精确控制和对反应物料以精确配比瞬间混合，因此微反应器的传质效率非常高，且为连续式反应，能够大大缩短工时，相比传统缩短了5-8个小时，缩短反应的同时</description><language>chi ; eng</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; SUGARS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191011&DB=EPODOC&CC=CN&NR=110317236A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191011&DB=EPODOC&CC=CN&NR=110317236A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TIAN ZHENPING</creatorcontrib><creatorcontrib>XIA HOUQI</creatorcontrib><creatorcontrib>LIU QUANCAI</creatorcontrib><creatorcontrib>KONG MEI</creatorcontrib><creatorcontrib>NING SHUQUN</creatorcontrib><creatorcontrib>FANG MINGFENG</creatorcontrib><creatorcontrib>MA QINGZHU</creatorcontrib><title>Method for continuously preparing tulathromycin by adopting microchannel reactor</title><description>The invention relates to a method for continuously preparing tulathromycin by adopting a microchannel reactor. By adopting the microchannel reactor which has a large specific surface area to continuously prepare tulathromycin, the advantages are brought that the heat exchange efficiency and the mixing efficiency are extremely high, and precise temperature control and instantaneous mixing of reaction materials in a precise ratio can be achieved, so that the mass transfer efficiency of the microchannel reactor is very high; continuous reaction is achieved by adopting the microchannel reactor sothat working hours can be greatly shortened by 5-8 hours compared with that of the conventional method, the conversion rate is increased while reaction is shortened, by-products (ring-opening impurities) are reduced, and the purity of the product is improved.
本发明涉及一种利用微通道反应器连续式制备泰拉霉素的方法，该方法利用微通道反应器连续式制备泰拉霉素，微通道反应器有极大的比表面积，由此带来的优势是极大的换热效率和混合效率，能实现对温度的精确控制和对反应物料以精确配比瞬间混合，因此微反应器的传质效率非常高，且为连续式反应，能够大大缩短工时，相比传统缩短了5-8个小时，缩短反应的同时</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyjEKwkAQQNFtLES9w3gAwRjQWoJio1jYh3EzSRY2M8vspNjbi-ABrH7x_tI972SjdNCLghe2wLPMORZISgk18AA2R7RRZSo-MLwLYCfJvjIFr-JHZKYISuhNdO0WPcZMm19Xbnu9vJrbjpK0lBN6YrK2eVTVvq5Oh_p4rv95PjPtOHo</recordid><startdate>20191011</startdate><enddate>20191011</enddate><creator>TIAN ZHENPING</creator><creator>XIA HOUQI</creator><creator>LIU QUANCAI</creator><creator>KONG MEI</creator><creator>NING SHUQUN</creator><creator>FANG MINGFENG</creator><creator>MA QINGZHU</creator><scope>EVB</scope></search><sort><creationdate>20191011</creationdate><title>Method for continuously preparing tulathromycin by adopting microchannel reactor</title><author>TIAN ZHENPING ; XIA HOUQI ; LIU QUANCAI ; KONG MEI ; NING SHUQUN ; FANG MINGFENG ; MA QINGZHU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN110317236A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>TIAN ZHENPING</creatorcontrib><creatorcontrib>XIA HOUQI</creatorcontrib><creatorcontrib>LIU QUANCAI</creatorcontrib><creatorcontrib>KONG MEI</creatorcontrib><creatorcontrib>NING SHUQUN</creatorcontrib><creatorcontrib>FANG MINGFENG</creatorcontrib><creatorcontrib>MA QINGZHU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TIAN ZHENPING</au><au>XIA HOUQI</au><au>LIU QUANCAI</au><au>KONG MEI</au><au>NING SHUQUN</au><au>FANG MINGFENG</au><au>MA QINGZHU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Method for continuously preparing tulathromycin by adopting microchannel reactor</title><date>2019-10-11</date><risdate>2019</risdate><abstract>The invention relates to a method for continuously preparing tulathromycin by adopting a microchannel reactor. By adopting the microchannel reactor which has a large specific surface area to continuously prepare tulathromycin, the advantages are brought that the heat exchange efficiency and the mixing efficiency are extremely high, and precise temperature control and instantaneous mixing of reaction materials in a precise ratio can be achieved, so that the mass transfer efficiency of the microchannel reactor is very high; continuous reaction is achieved by adopting the microchannel reactor sothat working hours can be greatly shortened by 5-8 hours compared with that of the conventional method, the conversion rate is increased while reaction is shortened, by-products (ring-opening impurities) are reduced, and the purity of the product is improved.
本发明涉及一种利用微通道反应器连续式制备泰拉霉素的方法，该方法利用微通道反应器连续式制备泰拉霉素，微通道反应器有极大的比表面积，由此带来的优势是极大的换热效率和混合效率，能实现对温度的精确控制和对反应物料以精确配比瞬间混合，因此微反应器的传质效率非常高，且为连续式反应，能够大大缩短工时，相比传统缩短了5-8个小时，缩短反应的同时</abstract><oa>free_for_read</oa></addata></record> |
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| title | Method for continuously preparing tulathromycin by adopting microchannel reactor |
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