COMPOSITION COMPRISING BENZOIC ACID AMIDE COMPOUND AND SOLUBILIZING AGENT

The present specification relates to a skin external composition comprising: a solute which is a benzoic acid amide compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof; and at least one first solubilizing agent selected from among diethylen...

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Bibliographische Detailangaben
Hauptverfasser: KIM JEONG-HWAN, KO JAE-YOUNG, YI CHANG-GEUN, BAEK HEUNG-SOO, CHOI JOON-HO, KIM SU-IL, SHIN HONG-JU, LIM HYUNG-JUN, JEONG YEON-SU, LEE CHANG-SEOK, JOO YUNG-HYUP
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present specification relates to a skin external composition comprising: a solute which is a benzoic acid amide compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof; and at least one first solubilizing agent selected from among diethylene glycol monoethyl ether, methyl gluceth, glycerol ether, polyethylene glycol, and a polyethylene glycol/propylene glycol copolymer, and provides a skin external composition with improved solubility and feeling of use. 本说明书涉及一种包括溶质的皮肤外用组合物,该溶质为苯甲酸酰胺化合物、该化合物的同分异构体、该化合物的药学上可接受的盐、该化合物的水合物、或是该化合物的溶剂化物;以及第一增溶剂,其为二乙二醇单乙醚、甲基葡糖醇聚醚、甘油醚、聚乙二醇、以及聚乙二醇/聚丙二醇的共聚合物的至少一种,且本说明书提供一种改良的溶解度及使用感的皮肤外用组合物。