Preparation method for reducing toxic and side effect of daphne giraldii injection

The invention discloses a preparation method for reducing the toxic and side effect of cortex daphnes injection. The preparation method mainly comprises the following steps of: taking medicinal partsof daphne giraldii; after cleansing and crushing, carrying out refluxing extraction by utilizing a chloroform-acetone mixed solvent; extracting and eluting through silica-gel column chromatography; then concentrating and eluting with a neutral aluminum oxide column again; detecting the purity of effective components through high performance liquid chromatography; collecting a daphne giraldii totalcoumarin eluting solution; adding pharmaceutically acceptable conventional auxiliary materials to prepare pharmaceutically acceptable traditional Chinese medicine injection. The preparation method disclosed by the invention is simple and a technology is reasonable, so that the toxic and side effect of the cortex daphnes is remarkably reduced; the effective components of the daphne giraldii injection are purified to the gr