BACTERIAL STRAIN PRODUCING 2,3-BUTANEDIOL AND OTHER METABOLITES
The present invention provides a modified strain of the bacterium Lactococcus lactis obtainable by a method that comprises a step of fusion of two protoplasts from two Lactococcus lactis parental strains which, compared to the wild type strain of Lactococcus lactis from which they derive, show: (a)...
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| creator | OCHOA GOMEZ JOSE RAMON RONCAL MARTINEZ TOMAS DIAZ DE GUERENU ZABARTE MARIA DEL MAR PRIETO FERNANDEZ SORAYA RINCON ARROYO INES CABALLERO ROMAN SUSANA |
| description | The present invention provides a modified strain of the bacterium Lactococcus lactis obtainable by a method that comprises a step of fusion of two protoplasts from two Lactococcus lactis parental strains which, compared to the wild type strain of Lactococcus lactis from which they derive, show: (a) an increased ability to produce acetoin and/or 2,3- butanediol (2,3-BDO), and (b) a decreased ability to produce lactic acid, when cultured under aerobic conditions, and wherein the modified strain of Lactococcus lactis has an increased ability to produce 2,3-BDO of at least 20 times the amount produced by the wild type strain, an increased ability to produce acetoin of at least 20 times the amount produced by the wild type strain and a decreased ability to produce lactic acid of at least 10 times the amount produced by the wild type strain, when cultured under aerobic conditions. Also provided are methods to produce acetoin and 2,3- BDO..
本发明提供了通过以下方法获得的细菌乳酸乳球菌的改良菌株，所述方法包括将来自两种乳酸乳球菌亲本菌株的两个原生质体融合的步骤，当在需氧条件下培养时，所述乳酸 |
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本发明提供了通过以下方法获得的细菌乳酸乳球菌的改良菌株，所述方法包括将来自两种乳酸乳球菌亲本菌株的两个原生质体融合的步骤，当在需氧条件下培养时，所述乳酸</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190402&DB=EPODOC&CC=CN&NR=109563471A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190402&DB=EPODOC&CC=CN&NR=109563471A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>OCHOA GOMEZ JOSE RAMON</creatorcontrib><creatorcontrib>RONCAL MARTINEZ TOMAS</creatorcontrib><creatorcontrib>DIAZ DE GUERENU ZABARTE MARIA DEL MAR</creatorcontrib><creatorcontrib>PRIETO FERNANDEZ SORAYA</creatorcontrib><creatorcontrib>RINCON ARROYO INES</creatorcontrib><creatorcontrib>CABALLERO ROMAN SUSANA</creatorcontrib><title>BACTERIAL STRAIN PRODUCING 2,3-BUTANEDIOL AND OTHER METABOLITES</title><description>The present invention provides a modified strain of the bacterium Lactococcus lactis obtainable by a method that comprises a step of fusion of two protoplasts from two Lactococcus lactis parental strains which, compared to the wild type strain of Lactococcus lactis from which they derive, show: (a) an increased ability to produce acetoin and/or 2,3- butanediol (2,3-BDO), and (b) a decreased ability to produce lactic acid, when cultured under aerobic conditions, and wherein the modified strain of Lactococcus lactis has an increased ability to produce 2,3-BDO of at least 20 times the amount produced by the wild type strain, an increased ability to produce acetoin of at least 20 times the amount produced by the wild type strain and a decreased ability to produce lactic acid of at least 10 times the amount produced by the wild type strain, when cultured under aerobic conditions. Also provided are methods to produce acetoin and 2,3- BDO..
本发明提供了通过以下方法获得的细菌乳酸乳球菌的改良菌株，所述方法包括将来自两种乳酸乳球菌亲本菌株的两个原生质体融合的步骤，当在需氧条件下培养时，所述乳酸</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLB3cnQOcQ3ydPRRCA4JcvT0UwgI8ncJdfb0c1cw0jHWdQoNcfRzdfH091Fw9HNR8A_xcA1S8HUNcXTy9_EMcQ3mYWBNS8wpTuWF0twMim6uIc4euqkF-fGpxQWJyal5qSXxzn6GBpamZsYm5oaOxsSoAQBg4yok</recordid><startdate>20190402</startdate><enddate>20190402</enddate><creator>OCHOA GOMEZ JOSE RAMON</creator><creator>RONCAL MARTINEZ TOMAS</creator><creator>DIAZ DE GUERENU ZABARTE MARIA DEL MAR</creator><creator>PRIETO FERNANDEZ SORAYA</creator><creator>RINCON ARROYO INES</creator><creator>CABALLERO ROMAN SUSANA</creator><scope>EVB</scope></search><sort><creationdate>20190402</creationdate><title>BACTERIAL STRAIN PRODUCING 2,3-BUTANEDIOL AND OTHER METABOLITES</title><author>OCHOA GOMEZ JOSE RAMON ; RONCAL MARTINEZ TOMAS ; DIAZ DE GUERENU ZABARTE MARIA DEL MAR ; PRIETO FERNANDEZ SORAYA ; RINCON ARROYO INES ; CABALLERO ROMAN SUSANA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN109563471A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2019</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>OCHOA GOMEZ JOSE RAMON</creatorcontrib><creatorcontrib>RONCAL MARTINEZ TOMAS</creatorcontrib><creatorcontrib>DIAZ DE GUERENU ZABARTE MARIA DEL MAR</creatorcontrib><creatorcontrib>PRIETO FERNANDEZ SORAYA</creatorcontrib><creatorcontrib>RINCON ARROYO INES</creatorcontrib><creatorcontrib>CABALLERO ROMAN SUSANA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>OCHOA GOMEZ JOSE RAMON</au><au>RONCAL MARTINEZ TOMAS</au><au>DIAZ DE GUERENU ZABARTE MARIA DEL MAR</au><au>PRIETO FERNANDEZ SORAYA</au><au>RINCON ARROYO INES</au><au>CABALLERO ROMAN SUSANA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BACTERIAL STRAIN PRODUCING 2,3-BUTANEDIOL AND OTHER METABOLITES</title><date>2019-04-02</date><risdate>2019</risdate><abstract>The present invention provides a modified strain of the bacterium Lactococcus lactis obtainable by a method that comprises a step of fusion of two protoplasts from two Lactococcus lactis parental strains which, compared to the wild type strain of Lactococcus lactis from which they derive, show: (a) an increased ability to produce acetoin and/or 2,3- butanediol (2,3-BDO), and (b) a decreased ability to produce lactic acid, when cultured under aerobic conditions, and wherein the modified strain of Lactococcus lactis has an increased ability to produce 2,3-BDO of at least 20 times the amount produced by the wild type strain, an increased ability to produce acetoin of at least 20 times the amount produced by the wild type strain and a decreased ability to produce lactic acid of at least 10 times the amount produced by the wild type strain, when cultured under aerobic conditions. Also provided are methods to produce acetoin and 2,3- BDO..
本发明提供了通过以下方法获得的细菌乳酸乳球菌的改良菌株，所述方法包括将来自两种乳酸乳球菌亲本菌株的两个原生质体融合的步骤，当在需氧条件下培养时，所述乳酸</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | BACTERIAL STRAIN PRODUCING 2,3-BUTANEDIOL AND OTHER METABOLITES |
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