Method for effectively inhibiting synthesis of N-Hydroxyacetylneuraminic acid in meat product

The invention discloses a method for effectively inhibiting synthesis of N-Hydroxyacetylneuraminic acid in meat products. The method comprises: administering a live animal to a meat product, and administering the skin as a suede by oral administration. The compound was prepared into a 1 mL solution...

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Hauptverfasser: LI HONGYING, YAN YINXUE, LIANG MEILIAN, XU AQI, ZENG XUEFENG, ZHU QIUJING, ZHOU YINGZI, CHANG RUI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a method for effectively inhibiting synthesis of N-Hydroxyacetylneuraminic acid in meat products. The method comprises: administering a live animal to a meat product, and administering the skin as a suede by oral administration. The compound was prepared into a 1 mL solution using a 0.5% sodium carboxymethylcellulose solution, and the amount of perfusion was 1 mL/d, and thestomach was administered for 29 to 31 days. The invention adopts the natural flavonoid quercetin to inhibit the substrate of CMP-Neu5Ac hydroxylase, thereby affecting the activity of CMP-Neu5Ac hydroxylase, thereby reducing the synthesis of Neu5Gc, and performing N-hydroxyacetate nerve from the pre-slaughter living body. The intervention of biochemical synthesis of acid is low in cost and the effect is more obvious. 本发明公开了种有效抑制肉制品中N-羟乙酰神经氨酸合成的方法,该方法为:对待宰肉制品活体动物灌药,通过经口给药途径灌胃方式,给药为槲皮素,将其采用0.5%的羧甲基纤维素钠溶液进行配制成1mL溶液,每次灌胃量为1mL/d,灌胃29-31d。本发明采用天然的黄酮类物质槲皮素抑制CMP-Neu5Ac羟化酶的底物,进而影响CMP-Neu5Ac羟化酶的活性,达到减少Neu5Gc的合成,从宰前活体中进行N-羟乙酰神经氨