Genetically modified T cell culture device and method for clinical application of cellular immunotherapy
The invention provides a genetically modified T cell culture device for clinical application of cellular immunotherapy. The genetically modified T cell culture device for the clinical application of the cellular immunotherapy can achieve stable production quality of T cells. The genetically modified...
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| creator | LI ZHILIANG BAI ZHONGHU NIE JIANQI JIN KUIQI SUN YANG |
| description | The invention provides a genetically modified T cell culture device for clinical application of cellular immunotherapy. The genetically modified T cell culture device for the clinical application of the cellular immunotherapy can achieve stable production quality of T cells. The genetically modified T cell culture device for the clinical application of the cellular immunotherapy is characterized by comprising a cell culture reactor, a cell culture box, a reagent storage mechanism, a reagent collecting mechanism, a cell separating mechanism, pipeline and conveying mechanisms and a controller, wherein the cell culture reactor comprises a tank for cell culture and a mixing mechanism for mixing liquid in the tank; the reagent storage mechanism comprises a mononuclear cell storage unit, a culture medium storage unit, a magnetic bead A storage unit, a solution A storage unit, a magnetic bead B storage unit, a solution B storage unit, a virus storage unit, an IL-2 storage unit and a T cell preservation solution stor |
| format | Patent |
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The genetically modified T cell culture device for the clinical application of the cellular immunotherapy can achieve stable production quality of T cells. The genetically modified T cell culture device for the clinical application of the cellular immunotherapy is characterized by comprising a cell culture reactor, a cell culture box, a reagent storage mechanism, a reagent collecting mechanism, a cell separating mechanism, pipeline and conveying mechanisms and a controller, wherein the cell culture reactor comprises a tank for cell culture and a mixing mechanism for mixing liquid in the tank; the reagent storage mechanism comprises a mononuclear cell storage unit, a culture medium storage unit, a magnetic bead A storage unit, a solution A storage unit, a magnetic bead B storage unit, a solution B storage unit, a virus storage unit, an IL-2 storage unit and a T cell preservation solution stor</description><language>chi ; eng</language><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20181221&DB=EPODOC&CC=CN&NR=109055222A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25566,76549</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20181221&DB=EPODOC&CC=CN&NR=109055222A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LI ZHILIANG</creatorcontrib><creatorcontrib>BAI ZHONGHU</creatorcontrib><creatorcontrib>NIE JIANQI</creatorcontrib><creatorcontrib>JIN KUIQI</creatorcontrib><creatorcontrib>SUN YANG</creatorcontrib><title>Genetically modified T cell culture device and method for clinical application of cellular immunotherapy</title><description>The invention provides a genetically modified T cell culture device for clinical application of cellular immunotherapy. The genetically modified T cell culture device for the clinical application of the cellular immunotherapy can achieve stable production quality of T cells. The genetically modified T cell culture device for the clinical application of the cellular immunotherapy is characterized by comprising a cell culture reactor, a cell culture box, a reagent storage mechanism, a reagent collecting mechanism, a cell separating mechanism, pipeline and conveying mechanisms and a controller, wherein the cell culture reactor comprises a tank for cell culture and a mixing mechanism for mixing liquid in the tank; the reagent storage mechanism comprises a mononuclear cell storage unit, a culture medium storage unit, a magnetic bead A storage unit, a solution A storage unit, a magnetic bead B storage unit, a solution B storage unit, a virus storage unit, an IL-2 storage unit and a T cell preservation solution stor</description><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjj0KwkAQRtNYiHqH8QBCjKSwlOBPZZU-DLuzZGB2Z9nsCrm9RjyA1feK9-BbV-OdAmU2KDKDV8uOyUIPhkTAFMklEVh6sSHAYMFTHtWC0wRGOCwhYIzygcwaQN03LYIJ2PsSNI-UMM7bauVQJtr9dlPtb9e-exwo6kBTRLMcGbrnsT7Xbds0zeX0j_MGBeBAhg</recordid><startdate>20181221</startdate><enddate>20181221</enddate><creator>LI ZHILIANG</creator><creator>BAI ZHONGHU</creator><creator>NIE JIANQI</creator><creator>JIN KUIQI</creator><creator>SUN YANG</creator><scope>EVB</scope></search><sort><creationdate>20181221</creationdate><title>Genetically modified T cell culture device and method for clinical application of cellular immunotherapy</title><author>LI ZHILIANG ; BAI ZHONGHU ; NIE JIANQI ; JIN KUIQI ; SUN YANG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN109055222A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2018</creationdate><topic>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>LI ZHILIANG</creatorcontrib><creatorcontrib>BAI ZHONGHU</creatorcontrib><creatorcontrib>NIE JIANQI</creatorcontrib><creatorcontrib>JIN KUIQI</creatorcontrib><creatorcontrib>SUN YANG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LI ZHILIANG</au><au>BAI ZHONGHU</au><au>NIE JIANQI</au><au>JIN KUIQI</au><au>SUN YANG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Genetically modified T cell culture device and method for clinical application of cellular immunotherapy</title><date>2018-12-21</date><risdate>2018</risdate><abstract>The invention provides a genetically modified T cell culture device for clinical application of cellular immunotherapy. The genetically modified T cell culture device for the clinical application of the cellular immunotherapy can achieve stable production quality of T cells. The genetically modified T cell culture device for the clinical application of the cellular immunotherapy is characterized by comprising a cell culture reactor, a cell culture box, a reagent storage mechanism, a reagent collecting mechanism, a cell separating mechanism, pipeline and conveying mechanisms and a controller, wherein the cell culture reactor comprises a tank for cell culture and a mixing mechanism for mixing liquid in the tank; the reagent storage mechanism comprises a mononuclear cell storage unit, a culture medium storage unit, a magnetic bead A storage unit, a solution A storage unit, a magnetic bead B storage unit, a solution B storage unit, a virus storage unit, an IL-2 storage unit and a T cell preservation solution stor</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | Genetically modified T cell culture device and method for clinical application of cellular immunotherapy |
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