Novel compound 3-methyl-4,5-dichlorothiophene-2-carboxylic acid and preparation method thereof

Novel compound 3-methyl-4,5-dichlorothiophene-2-carboxylic acid and preparation method thereof

The invention discloses a novel compound 3-methyl-4,5-dichlorothiophene-2-carboxylic acid with the following structural formula defined in the specification. A preparation method of the compound 3-methyl-4,5-dichlorothiophene-2-carboxylic acid comprises the following steps: adding 3-methylthiophene-...

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Hauptverfasser: JIN QINGXIAN, WANG MINGHUA, XU FEN, HU LUPING, QIN XUDONG, ZHEN YAOYAO
Format: Patent
Sprache:chi ; eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator JIN QINGXIAN
WANG MINGHUA
XU FEN
HU LUPING
QIN XUDONG
ZHEN YAOYAO
description The invention discloses a novel compound 3-methyl-4,5-dichlorothiophene-2-carboxylic acid with the following structural formula defined in the specification. A preparation method of the compound 3-methyl-4,5-dichlorothiophene-2-carboxylic acid comprises the following steps: adding 3-methylthiophene-2-carboxylic acid into an acetic acid and N,N-dimethylformamide mixed solution, adding N-chlorosuccinimide in ice bath, and carrying out a reaction at the temperature of 25-35 DEG C for 4-6 h to obtain 3-methyl-4,5-dichlorothiophene-2-carboxylic acid. The synthetic route disclosed by the invention is short and only comprises one step, the used preparation method is simple to operate, the reaction is relatively mild, the product is easily treated and purified, and the preparation method is a method suitable for batch preparation. As such the compound is a valuable functional intermediate, the compound disclosed by the invention has important research and practical value, and the preparation and production of other s
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HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Novel compound 3-methyl-4,5-dichlorothiophene-2-carboxylic acid and preparation method thereof
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