Method for using anions to catalyze hydrolysis of glycoside compound

The invention provides a method for using anions to catalyze hydrolysis of a glycoside compound. The method comprises the following steps of adding an anion solution and a solvent into a substrate glycoside at the reaction temperature of 30-130 DEG C for 0.5 h-24 h, and afterwards, purifying the rea...

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Hauptverfasser: XIAO YONGKUN, LUAN GUIHUA, WANG DONGMING
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creator XIAO YONGKUN
LUAN GUIHUA
WANG DONGMING
description The invention provides a method for using anions to catalyze hydrolysis of a glycoside compound. The method comprises the following steps of adding an anion solution and a solvent into a substrate glycoside at the reaction temperature of 30-130 DEG C for 0.5 h-24 h, and afterwards, purifying the reaction product. According to the method, a natural polysaccharide glycoside serves as the substrate,the anions are utilized to dynamically and controllably catalyze the natural glycoside, and the components of the low-glycosyl secondary nucleoside and aglycon are generated. The method is easy to operate and low in cost, and the process is easy to control. The purified product can be applied to development of medicine, healthcare products, food and cosmetics. 本发明提供了种阴离子催化水解苷类化合物的方法,包括如下步骤:向底物苷类中加入阴离子溶液、溶剂在反应温度为30~130℃的温度下反应0.5h~24h,之后将反应产物进行纯化。本发明所述的方法以多糖基天然苷类为底物,利用阴离子对天然苷类进行动态可控地催化,生成低糖基次苷、苷元等成分。该方法操作简单,成本低,过程易于控制。纯化后的产物可应用于药品、保健品、食品及化妆品的开发。
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The method comprises the following steps of adding an anion solution and a solvent into a substrate glycoside at the reaction temperature of 30-130 DEG C for 0.5 h-24 h, and afterwards, purifying the reaction product. According to the method, a natural polysaccharide glycoside serves as the substrate,the anions are utilized to dynamically and controllably catalyze the natural glycoside, and the components of the low-glycosyl secondary nucleoside and aglycon are generated. The method is easy to operate and low in cost, and the process is easy to control. The purified product can be applied to development of medicine, healthcare products, food and cosmetics. 本发明提供了种阴离子催化水解苷类化合物的方法,包括如下步骤:向底物苷类中加入阴离子溶液、溶剂在反应温度为30~130℃的温度下反应0.5h~24h,之后将反应产物进行纯化。本发明所述的方法以多糖基天然苷类为底物,利用阴离子对天然苷类进行动态可控地催化,生成低糖基次苷、苷元等成分。该方法操作简单,成本低,过程易于控制。纯化后的产物可应用于药品、保健品、食品及化妆品的开发。</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; STEROIDS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20180928&amp;DB=EPODOC&amp;CC=CN&amp;NR=108586412A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20180928&amp;DB=EPODOC&amp;CC=CN&amp;NR=108586412A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>XIAO YONGKUN</creatorcontrib><creatorcontrib>LUAN GUIHUA</creatorcontrib><creatorcontrib>WANG DONGMING</creatorcontrib><title>Method for using anions to catalyze hydrolysis of glycoside compound</title><description>The invention provides a method for using anions to catalyze hydrolysis of a glycoside compound. The method comprises the following steps of adding an anion solution and a solvent into a substrate glycoside at the reaction temperature of 30-130 DEG C for 0.5 h-24 h, and afterwards, purifying the reaction product. According to the method, a natural polysaccharide glycoside serves as the substrate,the anions are utilized to dynamically and controllably catalyze the natural glycoside, and the components of the low-glycosyl secondary nucleoside and aglycon are generated. The method is easy to operate and low in cost, and the process is easy to control. 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
title Method for using anions to catalyze hydrolysis of glycoside compound
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